Adenosquamous carcinoma of the head and neck (ASC) is a rare and aggressive variant of squamous cell carcinoma, a locally aggressive malignancy characterized by the presence of two distinct components: a squamous cell carcinoma and an adenocarcinoma. The purpose of this study was to report an additional rare case of adenosquamous carcinoma affecting the maxilla, with clinical microscopic featur...

Pancreatic cancer is one of the most lethal malignancies in the world and is the fourth highest cause of cancer deaths in the United States. According to the 2008 annual report of cancer statistics in Korea, malignant pancreatic cancer has the ninth highest incidence rate with a relative 5-year survival rate of 7.6%. The most common pancreatic histologic subtype is adenocarcinoma, which has a p...

Adenosquamous carcinoma is a rare malignant tumor with poor prognosis that is characterized histopathologically by the simultaneous presence of distinct areas of adenocarcinoma and squamous cell carcinoma. Until 2004, only 59 cases of adenosquamous carcinoma have been documented in English literatures in the head and neck region since the first one being reported in 1968. The present report is ...

BACKGROUND DeltaNp63 is an isoform of the p53 homolog p63, which lacks an amino-terminal transactivation domain. The aim of this study was to detect the deltaNp63 expression in the squamous carcinoma component of adenosquamous carcinoma and evaluate its usefulness as a specific squamous carcinoma marker. PATIENTS AND METHODS Immunohistochemistry was used to analyze the protein expression of d...

Adenosquamous carcinoma colon is a rare neoplasm of colon and is said to have an aggressive course and thus poorer prognosis. Here we have described a case of adenosquamous carcinoma colon in an elderly female patient, presenting with typical features of a colonic malignancy, but with a rapidly deteriorating clinical course and liver metastasis.

Adenosquamous carcinoma is a rare histologic subtype of extrahepatic bile duct (EBD) carcinoma and limited information is available on its clinicopathologic characteristics. Twelve cases of adenosquamous carcinoma were collected from 3 institutions and their clinicopathologic characteristics were examined and compared with those of 176 EBD adenocarcinomas. The adenocarcinoma component was more ...

BACKGROUND Adenosquamous carcinoma is a rare and aggressive form of lung cancer. The prognostic and predictive value of preoperative serum tumor markers and frequency of EGFR mutations in adenosquamous lung carcinoma are unclear. METHODS We retrospectively analyzed data and samples collected from 106 radically resected adenosquamous lung carcinoma patients with pathological stage I-IIIA betwe...

adenocarcinomas. Adenosquamous carcinomas with consisting of both glandular and squamous histologic components are a rare malignancy of the colon and rectum. This tumor type was originally described by Herheimer in 1907. Subsequent reports of adenosquamous carcinomas of the rectum and/or colon are limited as the estimated incidence of adenosquamous carcinomas of the colon and rectum is approxim...

Adenosquamous carcinoma is a rare tumor with coexisting elements of infiltrating squamous cell carcinoma and adenocarcinoma. This tumor is reported to arise in different organs but rarely in the oesophagus. In most cases, it shows highly aggressive biological behaviour with high propensity to regional lymph-node metastasis and poor prognosis. We describe the management of a patient with an aggr...

Adenosquamous carcinoma of the pancreas is a rare variant of pancreatic exocrine carcinoma. We report a case of 70 year old man who came to our hospital with abdominal pain, anorexia and jaundice. Imaging of the abdomen showed a mass in the region of the head of the pancreas. Histological evaluation of the pancreatic tumor showed an adenosquamous carcinoma which was extensively infiltrative wit...