This small book is an attempt to review present knowledge on the morphology, immunology, and pathogenicity of the pleuropneumonia-like organisms (PPLO). The author is a recognized authority on these organisms and the material is presented from her point of view, although she readily admits that there are some who may be in disagreement with her conclusions. Four of the eleven chapters are devot...

The study draws attention to the possibility of falsely positive and negative results obtained by commercial test for detection of Mycoplasma hominis in clinical samples. Material/Methods: 5,715 samples were compared using the Mycoplasma IST 2 kit (BioMerieux) with conventional culture on PPLO (pleuropneumonia like organism) media. The discordant results were verified by PCR method using primer...

In this study, the authors examined the technical performance of culture methodology using specific media: Mycoplasma isolation media of pleuropneumonia-like organisms (PPLO) broth and PPLO agar. Digitonin sensitivity, growth inhibition, the serum plate agglutination test, a commercially available enzyme-linked immunosorbent assay (ELISA) and a commercially available simplex polymerase chain re...

Seven of eight strains of Mycoplasma (PPLO) were found to be sensitive to the deoxystreptamines, certain macrolides, and the tetracyclines. These antibiotics are relative noncytotoxic. Kanamycin and tetracycline were useful in eliminating PPLO (pleuropneumonia-like organisms) strain Squibb no. 1 from a HeLa cell line which was deliberately contaminated with PPLO. Repeated exposure of M. laidlaw...

Pleuropneumonia-like organisms (PPLO) have frequently been isolated from the human genital tract since the first report by Dienes and Edsall (1937); their presence in the urethral discharge of patients with non-gonococcal urethritis (N.G.U.) aroused interest because of the unknown aetiology of the disease. The significance ofPPLO in the genital tract and their association with N.G.U. are disput...

Attempts to produce in animals conditions resembling various rheumatic diseases have been numerous and have employed a wide variety of agents. Such work has usually had as its object the investigation of the part played by a certain factor in the causation of rheumatic conditions or the provision of animal subjects to test the efficacy of therapeutic agents. The work reported here was undertake...

Pleuropneumonia-like organisms (PPLO) have frequently been isolated from the human genital tract since the first report by Dienes and Edsall (1937); their presence in the urethral discharge of patients with non-gonococcal urethritis (N.G.U.) aroused interest because of the unknown aetiology of the disease. The significance ofPPLO in the genital tract and their association with N.G.U. are disput...

This small book is an attempt to review present knowledge on the morphology, immunology, and pathogenicity of the pleuropneumonia-like organisms (PPLO). The author is a recognized authority on these organisms and the material is presented from her point of view, although she readily admits that there are some who may be in disagreement with her conclusions. Four of the eleven chapters are devot...