Abl is an essential regulator of cell migration and morphogenesis in both vertebrates and invertebrates. It has long been speculated that the adaptor protein Disabled (Dab), which is a key regulator of neuronal migration in the vertebrate brain, might be a component of this signaling pathway, but this idea has been controversial. We now demonstrate that null mutations of Drosophila Dab result i...

PURPOSE The novel fusion protein, DAB(389)EGF, is composed of both the catalytic and the translocation domains of diphtheria toxin that are fused to the human EGF, providing a targeting and a toxicity component. We tested DAB(389)EGF for antitumor activity in both in vitro and in vivo urinary bladder cancer models. EXPERIMENTAL DESIGN Human bladder cancer lines were treated with DAB(389)EGF a...

A serious problem affecting the local radio industry in Cyprus is interference from Middle East. This especially acute on highway along coast during summer months because degrades sound quality vehicle receivers due to chirping noise, hissing, fading and distortion. During last decade issue was explored by monitoring field strength intensity of unwanted signals with respect atmospheric conditio...

Taxanes, which are widely used in treatment of numerous cancer types, are well-known to induce hypersensitivity reactions (HSR), especially in the case of paclitaxel. Although the cause of the HSR is commonly thought to be a non-immunological direct effect of the diluent which is used to dissolve paclitaxel, some reports suggest the possibility of the presence of an immunological reaction to th...

Male and Female Swiss mice received, by subcutaneous injection on each of the First 5 days of life, 200 mg 4-dimethylaminoazobenzene (DAB), 2-methyl-4-dimethylaminoazobenzene (2-methyl-DAB), or 3'-methyl-4-dimethylaminoazobenzene (3'-methyl-DAB). A control group was similarly treated with the vehicle, 0.02 ml arachis oil. Between 50 and 56 mice in each group survived until the experiment was te...

The impedance-based criterion has turned out to be a very effective tool for the stability analysis of dual active bridge (DAB) converter with its input LC filter. While impedance DAB is highly dependent on modulation methods, influences methods impedances converters are still not clear. To close this gap, three typical converters, traditional single-phase-shift (SPS), dual-phase-shift (DPS) an...

RNA polymerase activity of liver nuclei; and (c) whether the nitrofurans ameliorated 3'-Me-DAB-induced changes in RNA polymerase activity. The nitrofurans were 2-(2furyl)-3-(5-nitro-2-furyl)acrylamide and 2-amino-5-[2-(5nitro-2-furyl)-l-(2-furyl)vinyl-l-]-l ,3,4-oxadiazole. Male Donryu rats were fed 1 or 0.5 g of 3'-Me-DAB by being maintained on a diet containing 0.06% 3'-Me-DAB or 3'-Me-DAB pl...

The Eureka-147 Digital Audio Broadcasting (DAB) standard defines the ’dynamic labels’ data field for holding information about the transmission content. However, this information does not follow a well-defined structure since it is designed to carry text for direct output to displays, for human interpretation. This poses a problem when machine interpretation of DAB content information is desire...

DAB (digital audio broadcasting) is a radio system which is depends on EUREKA-147 project. This project was designed by the Members of European Broadcasting Union (EBU). DAB System depends on wireless communication. DAB channel estimation was designed by the OFDM technology that reduces cochannel interference and multipath fading. In this paper we have analyzed bit error rate performance v/s si...