We have used the data from the DIRECT project to search for new globular cluster candidates in the M31 and M33 galaxies. We have found 67 new objects in M31 and 35 in M33 and confirmed 38 and 16 previously discovered ones. A V I and BV I photometry has been obtained for all the clusters in M31 and M33 respectively. Luminosity functions have been constructed for the clusters in each galaxy and c...

The DIRECT project aims to determine direct distances to two important galaxies in the cosmological distance ladder – M31 and M33 – using detached eclipsing binaries (DEBs) and Cepheids. We present the results of the first large-scale CCD-based search for variables in M33. We have observed two fields located in the central region of M33 for a total of 95 nights on the F. L. Whipple Observatory ...

We present non-LTE analyses of four M33 early B-supergiant stars and five Galactic counterparts. This is the first time that B supergiants beyond the Magellanic Clouds are analyzed by means of detailed Non-LTE techniques. Among the M33 stars, new spectroscopic observations of B38 (ob21–108) are presented and the object is classified as B1Ia. The classification of another M33 star, B133, is chan...

The M33 galaxy is a nearby, relatively metal-poor, late-type spiral. Its proximity and almost face-on inclination means that it projects over a large area on the sky, making it an ideal candidate for wide-field CCD mosaic imaging. Photometry was obtained for more than 10 6 stars covering a 74 ′ × 56 ′ field centered on M33. Main sequence (MS), supergiant branch (SGB), red giant branch (RGB) and...

MEIS1 is a three-amino acid loop extension class homeodomain-containing homeobox (HOX) cofactor that plays key roles in normal hematopoiesis and leukemogenesis. Expression of Meis1 is rate-limiting in MLL-associated leukemias and potently interacts with Hox and NUP98-HOX genes in leukemic transformation to promote self-renewal and proliferation of hematopoietic progenitors. The oncogenicity of ...

We compare the number of detected 22 GHz H2O masers in the Local Group galaxies M31, M33, NGC 6822, IC 10, IC 1613, DDO 187, GR8, NGC 185, and the Magellanic Clouds with the water maser population of the Milky Way. To accomplish this we searched for water maser emission in the two Local Group galaxies M33 and NGC 6822 using the Very Large Array (VLA) and incorporated results from previous studi...

In Drosophila, the products of the Polycomb group (Pc-G) of genes act as chromatin-associated multimeric protein complexes that repress expression of homeotic genes. Vertebrate Pc-G homologues have been identified, but the nature of the complexes they form and the mechanisms of their action are largely unknown. The Polycomb homologue M33 is implicated in mesoderm patterning in the mouse and her...

Using high-dispersion spectra from the HIRES echelle spectrograph on the Keck I telescope, we measure velocity dispersions for 4 globular clusters in M33. Combining the velocity dispersions with integrated photometry and structural parameters derived from King–Michie model fits to WFPC2 images, we obtain mass-to-light ratios for the clusters. The mean value is M/LV = 1.53 ± 0.18, very similar t...

In Drosophila, the trithorax-group and the Polycomb-group genes are necessary to maintain the expression of the homeobox genes in the appropriate segments. Loss-of-function mutations in those groups of genes lead to misexpression of the homeotic genes resulting in segmental homeotic transformations. Recently, mouse homologues of the Polycomb-group genes were identified including M33, the murine...

We have determined the distance to M33 using the tip of the red giant branch (TRGB) and the red clump (RC), from the V I photometry of stars in ten regions of M33 based onHST/WFPC2 images. The regions used in this study are located at R = 2.6 − 17.8 arcmin from the center of M33. The distance modulus to M33 obtained in this study, for an adopted foreground reddening of E(B − V ) = 0.04, is (m −...