نتایج جستجو برای: کمپلکس polycomb repressive complex2
تعداد نتایج: 11703 فیلتر نتایج به سال:
The Polycomb group (PcG) genes are required for maintenance of homeotic gene repression during development. Mutations in these genes can be suppressed by mutations in genes of the SWI/SNF family. We have purified a complex, termed PRC1 (Polycomb repressive complex 1), that contains the products of the PcG genes Polycomb, Posterior sex combs, polyhomeotic, Sex combs on midleg, and several other ...
Polycomb group (PcG) proteins are conserved chromatin regulators involved in the control of key developmental programs in eukaryotes. They collectively provide the transcriptional memory unique to each cell identity by maintaining transcriptional states of developmental genes. PcG proteins form multi-protein complexes, known as Polycomb repressive complex 1 (PRC1) and Polycomb repressive comple...
Chromatin modifying activities inherent to polycomb repressive complexes PRC1 and PRC2 play an essential role in gene regulation, cellular differentiation, and development. However, the mechanisms by which these complexes recognize their target sites and function together to form repressive chromatin domains remain poorly understood. Recruitment of PRC1 to target sites has been proposed to occu...
The self-renewal capacity of stem cells is crucial for the homeostatic maintenance of adult tissues, in which they mediate the continuous replacement of differentiated cells, and is the focus of attempts to design patient-specific therapies. The Polycomb group proteins are key global epigenetic regulators of stem-cell fate decisions. The Polycomb family induces histone-specific posttranslationa...
Estimated number of journal pages: 13.2 16 17 keywords: 18 19 TELOMERE REPEAT BINDING PROTEIN, genetic enhancer, LIKE 20 HETEROCHROMATIN PROTEIN 1, Polycomb Group, development, ChIP-seq 21 22 Synopsis 23 TELOMERE REPEAT BINDING PROTEINS sustain repression of target genes 24 they share with Polycomb Group Repressive Complexes. 25 Plant Cell Advance Publication. Published on December 31, 2015, do...
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