Objective: To identify the morphological varieties of the soft palate on a digital lateral cephalogram in the median sagittal plane which is presented variously in normal individuals with age and gender and also to assess if there exists any morphological variations in the soft palate among cleft palate and obstructive sleep apnea (OSA) groups. Materials and methods: A total of 120 normal subje...

The transcription factor TBX1 is a key mediator of developmental abnormalities associated with DiGeorge/Velocardiofacial Syndrome. Studies in mice have demonstrated that decreased dosage of Tbx1 results in defects in pharyngeal arch, cardiovascular, and craniofacial development. The role of Tbx1 in cardiac development has been intensely studied; however, its role in palatal development is poorl...

BACKGROUND Scapular tip osteomyogenous free flaps have been described for complex palate reconstruction. Minimal osteotomies are needed because of the similar shapes of the scapula and palate. We compared the bony morphology of the palate and scapular tip to determine the suitability of the scapular tip for palate reconstruction. METHODS We analyzed facial and chest CT images of 10 patients, ...

conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...

cleft lip and cleft palate are one of the most frequent congenital anomalies worldwide. this study was conducted in order to measure the frequency of cleft lip and palate among live births in akbar abadi hospital. this is a descriptive study, dealing with 57526 cases of live birth out of 59477 medical files in akbar abadi hospital from 2004 to 2008. all the collected data were recorded in speci...

Congenital tumors of the oral cavity are not common.Teratoids are the most common tumors, and in rare cases are associated with cleft soft palate. In this paper a rare case of Epignathus with cleft soft palate, bifida tongue, jaw malocclusion, tongue lipoma, Hypertelorism and low-set ears has been presented. A female infant with a large mass covered with skin and hair arising from hard palate, ...

(2001) Genetic heterogeneity and exclusion of a modifying locus at 17p11.2-p11.1 in Finnish families with van der Woude syndrome. (2001) Mapping of the second locus for the Van der Woude syndrome to chromosome 1p34. (2003) Collagen XI sequence variations in nonsyndromic cleft palate, Robin sequence and micrognathia. (2003) Linkage and linkage disequilibrium searched between non-syndromic cleft ...