Transforming growth factor-beta 3 (TGF-β3) is an important cytokine involved in various biological processes. TGF-β3 used as a scar-reducing antifibrotic agent for acute and chronic wounds fibrosing disorders. TGF-β3, valuable therapeutic protein, produced recombinantly different expression systems. the Escherichia coli (E. coli) system, widely due to its advantages recombinant production, comm...

Acellular dermal matrix (ADM) has been in clinical use for decades in numerous surgical applications. The ability for ADM to promote cellular repopulation, revascularisation and tissue regeneration is well documented. Adipose stem cells have the ability to differentiate into mesenchymal tissue types, including bone and cartilage. The aim of this study was to investigate the potential interactio...

Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a life-threatening inherited cardiomyopathy with an estimated prevalence of 1 per 5000 individuals characterized by the replacement of the cardiac myocytes with fibrofatty tissue leading to ventricular arrhythmias, right ventricular failure, and sudden cardiac death. ARVD/C is commonly inherited in an autosomal dominant manne...