Characterizing the transcriptome of defined hair follicle (HF) compartments and cell populations is a fundamental research challenge, which has already been mastered for murine HFs (www.hair-gel.net). Yet, comprehensive atlas human HF remains to be generated. As key step into this direction, we have used laser capture microdissection coupled with RNA sequencing reveal gene expression profiles 8...

While this is available for murine HFs (www.hair-gel.net), systematic characterization of the transcriptome specific human hair follicle (HF) compartments remains a major unmet challenge in research. Here, we have aimed to initiate generation such an atlas reveal HF compartment-specific transcriptome. We performed laser capture microdissection (LCM) on 8 selected compartments, i.e. bulge outer ...

Tan sheep (Ovis aries), a Chinese indigenous breed, has special curly fleece after birth, especially at one month old. However, this unique phenotype disappears gradually with age and the underlying reasons of trait evolvement are still unknown. In this study, skin transcriptome data was used to study this issue. In total 51,215 transcripts including described transcripts and transfrags were id...

We show that the topological Hochschild homology THH(R) of an En-ring spectrum R is an En−1-ring spectrum. The proof is based on the fact that the tensor product of the operad Ass for monoid structures and the the little n-cubes operad Cn is an En+1-operad, a result which is of independent interest. In 1993 Deligne asked whether the Hochschild cochain complex of an associative ring has a canoni...

The induction machine has many advantages: its specific power, its strength, relatively low manufacturing cost and minimal maintenance. But despite all these qualities, a number of faults can affect the life of the machine showing premature failures. The purpose of preventive maintenance in real time, we introduce a new signal processing technique based on HilbertHuang Transform (HHT) and margi...

Thl' l1larit1l' 1'11vironll1l'nt is the largest contiguous habitat on Earth; hllwl'vl'r, it is fill' frnm bdng homogeneous. Relevant ecological time and SPdL'l' Sl'ilil's span mUrl' than nine orders of magnitude (Figure 2.1; Dickey, ll)l) 1), t!1l'l'l'by contributing to the challenge of adequate and representatin' s.lmpling uf thl~ marine environment. Man;.' distinct marine ecosystems and their...

زمینه و هدف: کم‌تحرکی در مقابل آن تمرین جزء عوامل مرتبط با شاخص‌های آسیب کبدی به‌شمار می‌روند. وجود این هنوز نقش بسیاری از تمرین‌های ورزشی به‌ویژه تمرینات تناوبی مقاومتی مصرف برخی مکمل‌های غذایی جمله اسپیرولینا بر ایمنی التهابی کاملاٌ شناخته نشده است؛ بنابراین هدف پژوهش تعیین اثر هشت هفته مکمل‌دهی هوازی فعالیت بافت کبد بیان ژن CXCL1 عضلة موش‌های صحرایی نر بود.مواد روش‌ها: نیمه‌تجربی، 60 سر موش ن...

The purpose of this paper and its sequel is to determine the homotopy groups of the spectrum THH(`). Here p is an odd prime, ` is the Adams summand of p-local connective K-theory (see for example [25]) and THH is the topological Hochschild homology construction introduced by Bökstedt in [3]. In the present paper we will determine the mod p homotopy groups of THH(`) and also the integral homotop...