Cell-mediated antitumor effects have, in part, been attributed to the production of NO. Compounds which generate NO might, therefore, be useful in attenuating the growth of tumor cells. Six nitric oxide/nucleophile adducts that release NO spontaneously in solution were tested for their effectiveness in inhibiting DNA synthesis in A375 human melanoma cells. The complexes of NO with spermine, 3-(...

La implementación de rotación cultivos puede modificar las características físicas y químicas los suelos ha sido recomendada para mejorar la calidad este. En Colombia, algunos productores implementan diferentes sistemas en papa, siendo importante conocer el potencial que pueden aportar a estos productivos. El objetivo este trabajo fue evaluar del suelo después utilizar esquemas cultivos. Se eva...

We discuss high-performance programmable asynchronous pipeline arrays (PAPAs). These pipeline arrays are coarse-grain field programmable gate arrays (FPGAs) that realize high data throughput with fine-grain pipelined asynchronous circuits. We show how the PAPA architecture maintains most of the speed and energy benefits of a custom asynchronous design, while also providing post-fabrication logi...

In recent years, ethics has drawn increased interest from information technology and computer science practitioners as well as from academicians. This article investigates the issues outlined in the PAPA framework in today’s environment and explores the possibility that new issues have emerged. Findings indicate that the ethicality of property misuse may be viewed differently based on the level...

Evaluating the innovation of the Internet of Things: empirical evidence from the Intellectual Capital assessment Alan Murray Armando Papa Benedetta Cuozzo Giuseppe Russo Article information: To cite this document: Alan Murray Armando Papa Benedetta Cuozzo Giuseppe Russo , (2016),"Evaluating the innovation of the Internet of Things: empirical evidence from the Intellectual Capital assessment", B...

Anna Papa, Constantina Politis, Athina Tsoukala, Aikaterini Eglezou, Vassiliki Bakaloudi, Maria Hatzitaki, and Katerina Tsergouli Author affi liations: Aristotle University of Thessaloniki, Thessaloniki, Greece (A. Papa, K. Tsergouli); National Coordinating Haemovigilance Centre of the Hellenic Centre for Disease Control and Prevention, Athens, Greece (C. Politis); AHEPA University General Hosp...

Pyogenic Arthritis, Pyoderma Gangrenosum, and Acne Syndrome (PAPA syndrome) is an autoinflammatory disease caused by aberrant production of the proinflammatory cytokine interleukin-1. Mutations in the gene encoding proline serine threonine phosphatase-interacting protein-1 (PSTPIP1) have been linked to PAPA syndrome. PSTPIP1 is an adaptor protein that interacts with PYRIN, the protein encoded b...

C-type dorsal root ganglion (DRG) neurons express three types of Na+ currents: fast TTX-sensitive, slow TTX-resistant, and persistent TTX-resistant Na+ currents. The nitric oxide (NO) donors papa-NONOate and S-nitroso-N-acetyl-DL-penicillamine inhibit all three types of Na+ currents. The NO scavenger hemoglobin abolished the effects of papa-NONOate on Na+ currents, indicating that NO or NO-rela...

The mechanical behavior of individual P pili of uropathogenic Escherichia coli has been investigated using optical tweezers. P pili, whose main part constitutes the PapA rod, composed of approximately 10(3) PapA subunits in a helical arrangement, are distributed over the bacterial surface and mediate adhesion to host cells. They are particularly important in the pathogenesis of E. coli colonizi...

Cell-mediated antitumor effects have, in part, been attributed to the production of NO. Compounds which generate NO might, therefore, be useful in attenuating the growth of tumor cells. Six nitric oxide/nucleophile adducts that release NO spontaneously in solution were tested for their effectiveness in inhibiting DNA synthesis in A375 human melanoma cells. The complexes of NO with spermine, 3-(...