background: it is intriguing and imperative that the comparison of the iron preparations in hemodialysis (hd) patients. th is study aimed to observe the short-term effi cacy of parenteral iron sucrose and ferric chloride in hd patients. materials and methods: this was a consecutive 10-week single-blind study in taiwan. an intravenous iron supplement of 100 mg/week was administered as an infusio...

transfusion-dependent patients such as those suffering from β-thalassaemia develop a fatal secondary haemosiderosis and consequently a selective iron chelator must be used to relieve such iron overload. 3- hydroxypyridin-4-ones are selective for iron(iii) under most biological conditions, but unlike desferrioxamine, are efficiently absorbed when administered orally. in this study, the synthesis...

iron overload is a serious clinical condition which can be largely prevented by the use of iron-specific chelating agents. in this study, the synthesis and determination of partition coefficients (kpart) of a range of n-alkyl hydroxypyridinones, as orally active iron chelators, are described. synthesis of n-aryl hydroxypyridinones was achieved via a single step synthetic pathway. in this method...

background : it has been suggested that inflammatory state due to obesity can lead to alteration in iron metabolism. women in reproductive age are at higher risk of iron deficiency. in this study, we aimed to evaluate inflammatory status and iron markers in young overweight and obese women. subjects and methods: in this study, 120 young and healthy women with a bmi ≥ 25 kg/m2 were enrolled. bio...

abstract background: iron overload is a clinical consequence of repeated blood transfusions and causes significant organ damage, morbidity, and mortality in the absence of proper treatment. the primary targets of iron chelators used for treating transfusional iron overload are the prevention of iron ingress into tissues and its intracellular scavenging. the present study was aimed at elucidatin...

background: an increased oxidative stress in patients under treatment with high concentrations of oxygen (hyperoxia) is considered to be one of the major mechanisms of lung injury. between different mediators, transition metal ions especially iron, by generation of very reactive free radicals play an important role in oxidative stress process. disruption of normal iron hemostasis has been repor...

iron oxide is an important biological agent that has a key role in medical processes; however, the mechanism whereby it provides iron for human and animal cells and its biological uses remains unclear. we aimed to evaluate the effects of oral iron oxide on serum iron status and compare the results with those of iron sulfate as a reference salt. fifteen adult rabbits were divided into 3 groups o...

background: several studies have suggested that obesity-related inflammation can lead to altered iron metabolism as well as higher rates of iron deficiency in obese than in normal-weight subjects. given that at a population level, premenopausal women are at higher risk of iron deficiency, the purpose of this study was to investigate iron and inflammatory status in young overweight and obese wom...

iron deficiency in soil reduces the quality of durum wheat leading to fe deficiency in human. thus, this experiment investigated the effects of foliar application of nano-iron oxide (2 and 4 g l-1), iron chelate (edta), (4 and 8 g l-1), iron sulfate (4 and 8 g l-1), and the control on grain yield and quality, yield components, chlorophyll and carotenoids contents, peroxidase (pox), catalase (ca...