Abstract The full-heavy tetraquarks $$cc{\bar{c}}{\bar{b}}$$ c ¯ b and $$bb{\bar{b}}{\bar{c}}$$ are systematically investigated within a quark model. meson–meson structure, diquark–antidiquark structure K-structure considered in...

Bin-Amphiphysin-Rvs (BAR) domain proteins play essential roles in diverse cellular processes by inducing membrane invaginations or membrane protrusions. Among the BAR superfamily, the `classical' BAR and Fes/CIP4 homology BAR (F-BAR) subfamilies of proteins usually promote membrane invaginations, whereas the inverse BAR (I-BAR) subfamily generally incur membrane protrusions. Despite possessing ...

Bin-Amphiphysin-Rvs (BAR) domain proteins are central regulators of many cellular processes involving membrane dynamics. BAR domains sculpt phosphoinositide-rich membranes to generate membrane protrusions or invaginations. Here, we report that, in addition to regulating membrane geometry, BAR domains can generate extremely stable lipid microdomains by "freezing" phosphoinositide dynamics. This ...

N. E. Adam, J. P. Alexander, C. Bebek, B. E. Berger, K. Berkelman, F. Blanc, V. Boisvert, D. G. Cassel, P. S. Drell, J. E. Duboscq, K. M. Ecklund, R. Ehrlich, L. Gibbons, B. Gittelman, S. W. Gray, D. L. Hartill, B. K. Heltsley, L. Hsu, C. D. Jones, J. Kandaswamy, D. L. Kreinick, A. Magerkurth, H. Mahlke-Kruger, T. O. Meyer, N. B. Mistry, E. Nordberg, M. Palmer, J. R. Patterson, D. Peterson, J. ...

Drought stress is one of the serious problems that restricted agronomic plant production worldwide. In molecular level, the harmful effect of drought stress is mostly caused by producing of large amount of reactive oxygen species (ROS). Catalase and Metallothionein genes have a crucial role to mope the hydrogen peroxide (H2O2) resulting reducing oxidative damage. In this research the gene expre...

Endophilin and Sorting Nexin 9 (Snx9) play key roles in endocytosis by membrane curvature sensing and remodeling via their Bin/Amphiphysin/Rvs (BAR) domains. BAR and the related F-BAR domains form dimeric, crescent-shaped units that occur N- or C-terminally to other lipid-binding, adaptor, or catalytic modules. In crystal structures, the PX-BAR unit of Snx9 (Snx9(PX-BAR)) adopts an overall comp...

The effect of anti-sense RNA on the expression of the bialaphos resistance (bar) gene which encodes phosphinothricin acetyl transferase (PAT), was analysed in tobacco. Transient expression studies revealed that an anti-bar RNA with sequence complementarity to the complete bar coding region, inhibits PAT synthesis. To quantify the phenomenon, SR1 tobacco cells were transformed twice to introduce...