Increased interleukin (IL)-8 plays an important role not only in activation and recruitment of neutrophils but also in inducing exaggerated angiogenesis at the inflamed site. In the present study, we investigated the fact that clotrimazole (CLT) inhibits intestinal inflammation, and the inhibitory action is mediated through suppression of IL-8 expression. In the trinitrobenzene sulfonic acid (T...

We read with interest the recent Critical Care review of post-extubation laryngeal edema and stridor resulting in respiratory failure [1]. We mostly agree with the authors’ opinion in that article except that the cuff leak test (CLT) was proposed as a standard extubation algorithm. We have two reasons to disagree. First, although the CLT has been widely used for the prediction of post-extubatio...

BACKGROUND Cerenkov luminescence tomography (CLT) provides the three-dimensional (3D) radiopharmaceutical biodistribution in small living animals, which is vital to biomedical imaging. However, existing single-spectral and multispectral methods are not very efficient and effective at reconstructing the distribution of the radionuclide tracer. In this paper, we present a semi-quantitative Cerenk...

We have examined the effect of hydroxyurea (HU), clotrimazole (CLT), magnesium oxide (Mg), and combined CLT+Mg therapies on the erythrocyte characteristics and their response to chronic hypoxia in a transgenic sickle mouse (SAD) model. SAD mice were treated for 21 days with 1 of the following regimens (administered by gavage): control (n = 6), HU (200 mg/d; n = 6), CLT (80 mg/kg/d, n = 5), Mg (...

BACKGROUND We examine the clinical significance and biomarkers of tissue plasminogen activator (tPA)-catalyzed clot lysis time (CLT) in patients with intermediate-risk pulmonary embolism (PE). METHODS Platelet-poor, citrated plasma was obtained from patients with PE. Healthy age- and sex-matched patients served as disease-negative controls. Fibrinogen, α2-antiplasmin, plasminogen, thrombin ac...

It has been reported that papillary thyroid carcinoma (PTC) with chronic lymphocytic thyroiditis (CLT) is less associated with extrathyroidal extension (ETE), advanced tumor stage and lymph node (LN) metastasis. Other studies have suggested that concurrent CLT could antagonize PTC progression, even in BRAF-positive patients. Since the clinical significance of the BRAF mutation has been particul...

This paper focused on energy consumption and carbon emission for heating and cooling during a building’s operation stage, and examined the energy effects of using Cross Laminated Timber (CLT) as an alternative building material to reinforced concrete (RC) in China’s 31 key cities located in different climate zones. The authors designed two seven-story residential buildings, which were construct...

A positive integer n is called a CLT number if every group of order n satisfies the converse of Lagrange’s Theorem. In this note, we find all CLT and supersolvable numbers up to 1000. We also formulate some questions about the distribution of these numbers. RÉSUMÉ: Un nombre entier naturel n est appelé nombre CLT si tout groupe d’ordre n satisfait la réciproque du Théorme de Lagrange. Nous déte...

In recent work Cheon, Han, Lee, Ryu, and Stehlé presented an attack on the multilinear map of Coron, Lepoint, and Tibouchi (CLT). They show that given many low-level encodings of zero, the CLT multilinear map can be completely broken, recovering the secret factorization of the CLT modulus. The attack is a generalization of the “zeroizing” attack of Garg, Gentry, and Halevi. We first strengthen ...