Our goals were to (1) validate the parental Ages and Stages Questionnaires (ASQ) as a screening tool for psychomotor development among a cohort of ex-premature infants reaching 2 years, and (2) analyse the influence of parental socio-economic status and maternal education on the efficacy of the questionnaire. A regional population of 703 very preterm infants (<35 weeks gestational age) born bet...

Customizable endonucleases such as transcription activator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) enable rapid generation of mutant strains at genomic loci of interest in animal models and cell lines. With the accelerated pace of generating mutant alleles, genotyping has become a rate-limiting step...

OBJECTIVE Obesity is a growing epidemic and public health problem in children. The purpose of this study was to determine the effect of body mass index (BMI) on the gross motor development. MATERIALS & METHODS In this cross-sectional study conducted in 2012-13 in Gorgan, northern Iran, the gross motor development of 90 children 3-5 yr old in three groups of lean, normal and obese/overweight w...

BACKGROUND: Although preterm infants born at 29 to 36 gestational weeks (GW) are at risk for developmental delay, they do not always benefit from systematic follow-up. Primary care physicians are then responsible for their developmental surveillance and need effective screening tests. This study aimed to determine whether the Ages and Stages Questionnaires (ASQ) at 12 and 24 months’ corrected a...

The reformulated learned helplessness model claims that the tendency to explain bad events by internal, stable, and global causes potentiates quitting when bad events are encountered. We tested this prediction in the work setting with individuals who frequently experience bad events. Explanatory style, as measured by the Attributional Style Questionnaire (ASQ), correlated with and predicted the...

OBJECTIVE To evaluate the ability of Ages and Stages Questionnaire, a parent completed developmental screening questionnaire to detect developmental delay in Indian children. DESIGN Cross-sectional study. SETTING Child Development Clinic of a tertiary care center located in Northern India. PARTICIPANTS AND METHODS 200 children, 50 each in the age groups of 4±1, 10±1, 18±1 and 24±1 months ...

The psychometric properties of the Ages and Stages Questionnaire, Third Edition (ASQ-3) in a Colombian population were explored, including construct validity convergent validity. ASQ-3, its Spanish version, Escala de Abreviada del Desarrollo (Abbreviated Development Scale - EAD-3, by acronym Spanish) compared. Participants included 456 children selected at random from live births time period be...

BACKGROUND This study assessed the concurrent validity of the parent-completed developmental screening measure Ages and Stages Questionnaires, Third Edition (ASQ-3) compared with the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) in children born term, late preterm, or extremely preterm at 8, 18, or 30 months of corrected gestational ages (CGA). METHODS Data were ...

OBJECTIVE To prospectively examine whether children of women with a pregnancy affected by severe pre-eclampsia (PE), compared to children of women without a PE-affected pregnancy, have differences in neurodevelopmental performance up to 5 years of age. DESIGN Prospective cohort study. SETTING Tertiary care centre. PARTICIPANTS Women were recruited following a PE-affected pregnancy. After ...