Let R be a prime ring with center Z, I nonzero ideal of and D: × → symmetric bi–(α, α)-derivation d the trace D. In present paper, we have considered following conditions: i) [d(x), x]α,α = 0, ii)[d(x), ⊆ Cα,α, iii)(d(x), x)α,α iv)D1(d2(x), x) v)d1(d2(x)) f(x), for all x, y ∈ I, where D1 D2 are two bi-(α, α)-derivations, d1, d2 traces D1, respectively, B: is bi-additive mapping, f B.

We developed a sensitive competitive RT-PCR technique for quantitating the ratio of D2 to cyclophilin messenger RNA (mRNA) and used this to study type 2 deiodinase (D2) mRNA regulation. Hyperthyroidism in rats causes a 2- to 3-fold reduction in anterior pituitary and medial basal hypothalamus (MBH). Thyroid hormone (T3) withdrawal increased the D2/cyclophilin ratio 2- to 3-fold over 48 h in bot...

As well as catalyzing the conversion of cholesterol to pregnenolone for steroid synthesis, cytochrome P450scc (P450scc) can also metabolize vitamins D2 (D2) and D3 (D3). Two products of D2 metabolism by P450scc, 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2, have been identified and shown to exert biological activity on cultured keratinocytes. The aim of this study was to fully characteriz...

Dopamine D2 receptor interactions with arrestins and arrestin-dependent internalization have been characterized using heterologously expressed D2 receptor and arrestins. The purpose of this study was to investigate D2 receptor interaction with endogenous arrestins. Arrestin2 and arrestin3 in striatal homogenates bound to the third cytoplasmic loop of the D2 receptor, and purified arrestin2 and ...

In this paper, I present the modal adaptive logic AJ (based on S5) as well as the discussive logic D2 that is defined from it. D2 is the adaptive version of Jaśkowski’s paraconsistent system D2. Like D2, D2 validates all single-premise rules of Classical Logic. However, for formulas that behave consistently, D2 moreover validates all multiple-premise rules of Classical Logic. D2 thus leads to a...

2.1 The Case All di 6= 0 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2 The Case d0 = 0 < d1 ≤ d2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.3 The Case d0 < 0 = d1 < d2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 2.4 The Case d0 ≤ d1 < d2 = 0 . . . . . . . . . . . . . . . . . . . . . . . ...

Aberrant regulation of transition metals and the resultant disregulation of neuronal reactive oxygen species (ROS) are considered significant in the etiology of Alzheimer's disease (AD). We determined the solution structure of the D2 domain of APL-1 (APL1-D2), the Caenorhabditis elegans ortholog of the amyloid precursor protein domain 2 (APP-D2). The copper binding affinities of APL1-D2 and APP...

Chimeric D1/D2 receptors were constructed to identify structural determinants of drug affinity and efficacy. We previously reported that chimeras that had D1 receptor transmembrane domain VII together with amino-terminal sequence from the D2 receptor were nonfunctional. D2/D1 chimeras were constructed that contained D2 receptor sequence at the amino- and carboxyl-terminal ends and D1 receptor s...