Nothing in the immunological constitution of human red blood cells has grown so luxuriantly such a short time as the details of the Rh antigens (Rh 'factor', a haemagglutinogen, an antigen contained in the red blood cells). Six years ago there was one antigen, Rh, and two characters, (i) Rh positive, Rh, dominant and (w) Rh negative, rh, recessive. To-day there are three antigens and eight type...

The incidence of maternal Rh immunization in Rh-negative women following a single ABO compatible Rh-positive pregnancy is about 17%. This incidence was determined by following Rh-negative women through two Rh-incompatible pregnancies and analysing their sera for anti-Rh at the time of delivery of their second observed pregnancy. Maternal Rh immunization occurs almost exclusively after delivery;...

I describe and discuss the sometimes heated controversy surrounding the recognition heuristic (RH) as a model of inferential decision making. After briefly recapitulating the history of the RH up to its current version, I critically evaluate several specific assumptions and predictions of the RH and its surrounding framework: recognition as a memory-based process; the RH as a cognitive process ...

Rhesus (Rh) proteins were first identified in human erythroid cells and recently in other tissues. Like ammonia transporter (Amt) proteins, their only homologues, Rh proteins have the 12 transmembrane-spanning segments characteristic of transporters. Many think Rh and Amt proteins transport the same substrate, NH(3)/NH(4)(+), whereas others think that Rh proteins transport CO(2) and Amt protein...

Human Rhnu11 red blood cells fail to react with Rh antibodies, indicating that these cells are either devoid of Rh protein or, like other species, possess antigenically distinct variants. To determine whether Rhnull cells possess an Rh-like polypeptide, 32-kDa proteins from D--, rr, and Rhnull cells were labeled with the cysteine-specific probe, lZ61-labeled pyridyldithioethylamine. Size compar...

The visual photopigment rhodopsin (Rh) is a prototypical G protein-coupled receptor (GPCR) responsible for initiation of the phototransduction cascade in rod photoreceptors. Similar to other GPCRs, Rh can form dimers or even higher oligomers and tends to have a supramolecular organization that is likely important in the dim light response. Rh also exhibits high affinity for lipid rafts (i.e. ra...

BACKGROUND A woman's candidacy for Rh immune globulin depends on whether her blood type is Rh-positive (D antigen-positive) or Rh-negative (D antigen-negative). New molecular blood-typing methods have identified variant D antigens, which may be reported as Rh-positive or Rh-negative depending on the laboratory method. We describe a case illustrating the effect of the new laboratory methods on a...