A novel compound, KS-505a was isolated from the culture broth of a strain identified as Streptomyces argenteolus A-2. The compound inhibited bovine brain Ca2+ and calmodulin-dependent cyclic-nucleotide phosphodiesterase with an IC50 value (the concentration causing 50% inhibition) of 0.065 microM. The compound around that concentration had little or no effect on heart calmodulin-dependent and -...

The late Pliocene is notable for the appearance of two new hominid genera as well as the first archaeological sites, generally attributed to the Oldowan Industrial Complex. However, the behavioral ecology of Oldowan hominids has been little explored, particularly at sites older than 2.0 Ma. Moreover, debates on Oldowan hominid foraging ecology and behavior have centered on data from only two re...

در این مقاله یک مدل ریاضی برای مسئله سیستم تولیدی همکارانه ساخت بر اساس سفارش با رعایت انصاف تخصیص بار‌های تولید طراحی شده است. اهداف اصلی مدل، کمینه‌سازی هزینه‌‌های کل و حداکثر استفاده از منابع به‌منظور عادلانه شرایط عدم­قطعیت کنترل پارامتر‌های غیرقطعی روش برنامه‌ریزی فازی ‌شده نتایج نشان می‌دهد افزایش نرخ عدم‌قطعیت، می­یابد. ازآنجاکه ظرفیت کارخانه‌ها ثابت است، مقدار تقاضا، هر کارخانه نیز می­ی...

measurement of soil saturated hydraulic conductivity, ks, is normally affected by flow patterns such as macro pore; however, most current techniques do  not differentiate flow types, causing major problems in describing water and chemical flows within the soil matrix. this study compares eight models for scaling ks and predicted matrix and macro pore ks, using a database composed of 50 datasets...

Background The most common chromosomal abnormality due to non-obstructive azoospermia (NOA) is Klinefelter syndrome (KS) which occurs in 1-1.72 out of 500-1000 male infants. The probability of retrieving sperm as the outcome could be asymmetrically different between patients with and without KS, therefore logistic regression analysis is not a well-qualified test for this type of data. This stud...