The soluble proteins of a newborn human lens exhibit almost no non-tryptophan fluorescence. On aging, an increase in the fluorescence of all native crystallins is found except for 72-crystallin. With formation of nuclear cataract, a further increase is seen for 7,-crystallin. The fluorophore, excitation 355 nm/emission 420 nm, is mainly associated with one species of the Yi-crystallin populatio...

The survival of newborn babies depends on the care we provide. International agreements have affirmed the world’s commitment to improving newborn health, and recent global assessments have confirmed that doing so makes good social and economic sense. But newborn care often receives less-thanoptimum attention. Although child survival programs have helped reduce the death rate among children unde...

World Immunization Week 2016 is April 24–30. Coincidentally, on April 4 the Philippines launched a dengue immunization program targeting more than 1 million schoolchildren using the world's first dengue vaccine, CYD-TDV (Dengvaxia®). It took more than 20 years of research and development, including two Phase 3 clinical trials involving over 35,000 participants aged 2–16 years, for this new vacc...

Abstract We study whether institutional investors that sign the Principles for Responsible Investment (PRI), a commitment to responsible investing, exhibit better portfolio-level environmental, social, and governance (ESG) scores. Signatories outside of USA have superior ESG scores than nonsignatories, but US signatories at best similar ratings, worse if they underperformed recently, are retail...