نتایج جستجو برای: مارکرهای ویژه ssc

تعداد نتایج: 65978  

2012
Lan Ye Xianmin Su Zhengchang Wu Xianrui Zheng Jin Wang Chen Zi Guoqiang Zhu Shenglong Wu Wenbin Bao

Small RNA duodenal libraries were constructed for Escherichia coli F18-sensitive and -resistant weaned piglets in full-sib pair groups and sequenced using Illumina Solexa high-throughput sequencing technology. The identification of differentially expressed miRNAs provides the basis for improved database information on pig miRNAs, understanding the genetic basics of differences in resistance to ...

2016
Hack-Lyoung Kim

Recognition of pulmonary arterial hypertension (PAH) associated with systemic sclerosis (SSc) (SSc-PAH) is very important , because SSc-PAH is highly prevalent and is a leading cause of mortality in patients with SSc. 1)2) Despite the use of novel therapeutic strategies, response to PAH-targeted therapy is still insufficient in SSc-PAH, which is associated with poor prognosis in SSc-PAH. 3) Ind...

Journal: :Annals of the rheumatic diseases 2010
Y Hou B J Rabquer M L Gerber F Del Galdo S A Jimenez G K Haines W G Barr M C Massa J R Seibold A E Koch

OBJECTIVE To investigate the role of junctional adhesion molecule-A (JAM-A) in the pathogenesis of systemic sclerosis (SSc). METHODS Biopsy specimens from proximal and distal arm skin and serum were obtained from patients with SSc and normal volunteers. To determine the expression of JAM-A on SSc dermal fibroblasts and in SSc skin, cell surface ELISAs and immunohistology were performed. An EL...

Journal: :Annals of the rheumatic diseases 2009
O Kowal-Bielecka R Landewé J Avouac S Chwiesko I Miniati L Czirjak P Clements C Denton D Farge K Fligelstone I Földvari D E Furst U Müller-Ladner J Seibold R M Silver K Takehara B Garay Toth A Tyndall G Valentini F van den Hoogen F Wigley F Zulian Marco Matucci-Cerinic

PURPOSE The optimal treatment of systemic sclerosis (SSc) is a challenge because the pathogenesis of SSc is unclear and it is an uncommon and clinically heterogeneous disease affecting multiple organ systems. The aim of the European League Against Rheumatism (EULAR) Scleroderma Trials and Research group (EUSTAR) was to develop evidence-based, consensus-derived recommendations for the treatment ...

Journal: :Clinical and experimental rheumatology 2010
Dinesh Khanna Kevin K Brown Philip J Clements Robert Elashoff Daniel E Furst Jonathan Goldin James R Seibold Richard M Silver Donald P Tashkin Athol U Wells

Pulmonary disease is the leading cause of morbidity and mortality in patients with systemic sclerosis (SSc). Recent well-designed trials in SSc-associated interstitial lung disease (SSc-ILD) have provided important insights regarding outcome measures and trial design. Recent investigations into the pathogenesis of SSc-ILD have led to a renewed interest in assessing targeted therapies in SSc-ILD...

1993
J L Hewett T G Rizzo

We explore the possibility that Z ′ couplings can be probed using decay modes which involve neutrinos once Standard Model backgrounds are directly determined by the data itself. For some models, sufficient statistics are available at either the SSC or LHC to render these modes useful for coupling determina-tions, provided the mass of the Z ′ is not much larger than 1 TeV, if we assume other new...

2006
Lorinda Chung Christopher P. Denton Daniel E. Furst Dinesh Khanna Peter A. Merkel

1Departments of Medicine and Dermatology, Division of Immunology and Rheumatology, Stanford University and Palo Alto VA Health Care System, CA, USA; 2Centre for Rheumatology, Royal Free Hospital, London, United Kingdom; 3Department of Rheumatology, University Hospital Zurich, Switzerland; 4Department of Medicine, Division of Rheumatology, University of California at Los Angeles, Los Angeles, US...

2005
Laurent Candillier Isabelle Tellier Fabien Torre Olivier Bousquet

Résumé. Cet article se place dans le cadre du subspace clustering, dont la problématique est double : identifier simultanément les clusters et le sousespace spécifique dans lequel chacun est défini, et caractériser chaque cluster par un nombre minimal de dimensions, permettant ainsi une présentation des résultats compréhensible par un expert du domaine d’application. Les méthodes proposées jusq...

2009
L. Armus V. Desai M. Harwit G. Helou

P.N. Appleton (IPAC), A.W. Blain (Caltech), C.M. Bradford (JPL), C.R. Bridge (SSC), R. Chary (SSC), E. Daddi (CEA Saclay), V. Desai (SSC), M. Harwit (Cornell), G. Helou (IPAC), P.F. Hopkins (UC Berkeley), M. Malkan (UCLA), J. Melbourne (Caltech), E.J. Murphy (SSC), P. Ogle (SSC), C. Papovich (Texas A&M), A. Pope (NOAO), D. Riechers (Caltech), J.R. Rigby (OCIW), J.D. Smith (Toledo), G. Stacey (C...

2015
Akiko Tochimoto Yasushi Kawaguchi Hisashi Yamanaka

Systemic sclerosis (SSc) is a connective tissue disease that is characterized by tissue fibrosis, microvasculopathy, and autoimmunity. Interstitial lung disease (ILD) is a common complication of SSc and is one of the frequent causes of mortality in SSc. Although the exact etiology of SSc remains unknown, clinical and experimental investigations have suggested that genetic and environmental fact...

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