To date four OFAD (Optical Field Angle Distortion) calibrations have been performed on FGS3 in M35 and analyzed by the Astrometry Science Team. Two have been performed since the last HST (Hubble Space Telescope) Calibration Workshop. The ongoing Long Term Stability Tests have also been analyzed and incorporated into the calibration. A lateral color calibration has been derived from calibration ...

BACKGROUND Fibrinogen (Fg) has been considered essential for platelet aggregation. However, we recently demonstrated formation of occlusive thrombi in Fg-deficient mice and in mice doubly deficient for Fg and von Willebrand factor (Fg/VWF(-/-)). METHODS AND RESULTS Here we studied Fg/VWF-independent platelet aggregation in vitro and found no aggregation in citrated platelet-rich plasma of Fg/...

Haemophilus ducreyi is the etiologic agent of the sexually transmitted genital ulcer disease chancroid. In both natural and experimental chancroid, H. ducreyi colocalizes with fibrin at the base of the ulcer. Fibrin is obtained by cleavage of the serum glycoprotein fibrinogen (Fg) by thrombin to initiate formation of the blood clot. Fg binding proteins are critical virulence factors in medicall...

This study adopts the Keller’s ARCS (Attention, Relevance, Confidence, and Satisfaction) motivational design framework to develop instructional strategies to integrate educational game learning into formal classroom settings. The experimental instruction lasts 8 weeks and there are 103 students in 6 grader involved. From the result of students’ opinions, motivational instruction strategies deve...

Thrombospondin-1 (TSP) may, after secretion from platelet alpha granules, participate in platelet aggregation, but its mode of action is poorly understood. We evaluated the capacity of TSP to form inter-platelet cross-bridges through its interaction with fibrinogen (Fg), using either Fg-coated beads or Fg bound to the activated GPIIbIIIa integrin (GPIIbIIIa*) immobilized on beads or on activate...

The combined efficacy of space- and alertness related training in chronic hemineglect was tested behaviorally and in a longitudinal fMRI study. Earlier results had shown that both space as well as alertness related training as single intervention methods lead to short term improvement which, however, is not stable for longer time periods. The neurobiological data obtained in these studies revea...