OBJECTIVE Leukocyte immunoglobulin-like receptor 1 (LIR-1) is up-regulated by cytomegalovirus (CMV), which in turn, has been associated with premature aging and more severe joint disease in patients with rheumatoid arthritis (RA). The aim of this study was to investigate the expression and functional significance of LIR-1 in CMV-positive RA patients. METHODS We determined the phenotype, cytol...

In the framework of a systematic ALMA study IR-selected main-sequence and starburst galaxies at z~1-1.7 typical ~1" resolution, we report on effects mid-IR- X-ray-detected active galactic nuclei (AGN) reservoirs excitation molecular gas in sample 55 objects. We find detectable nuclear activity ~30% sample. The presence dusty tori influences IR SED galaxies, as highlighted by strong correlation ...

INTRODUCTION Dynamic predictors of fluid responsiveness have made automated management of fluid resuscitation more practical. We present initial simulation data for a novel closed-loop fluid-management algorithm (LIR, Learning Intravenous Resuscitator). METHODS The performance of the closed-loop algorithm was tested in three phases by using a patient simulator including a pulse-pressure varia...

Certain DNA sequence motifs and structures can promote genomic instability. We have explored instability induced in mouse cells by long inverted repeats (LIRs). A cassette was constructed containing a herpes simplex virus thymidine kinase (tk) gene into which was inserted an LIR composed of two inverted copies of a 1.1-kb yeast URA3 gene sequence separated by a 200-bp spacer sequence. The tk ge...

Objective: To elucidate the value of early computed tomographic (CT) signs of stroke in predicting the occlusion site in the cerebral arteries. Patients: 105 consecutive patients with acute embolic stroke affecting the anterior circulation. Methods: Four early signs were evaluated on cranial CT within six hours of stroke onset: loss of the insular ribbon (LIR); attenuation of the lentiform nucl...

HCN luminosity is a tracer of dense molecular gas, n(H2) > ∼3 × 10 cm, associated with star-forming giant molecular cloud (GMC) cores. We present the results and analysis of our survey of HCN emission from 65 infrared galaxies including 9 ultraluminous infrared galaxies (ULIGs, LIR > ∼10 L⊙), 22 luminous infrared galaxies (LIGs, 10 L⊙ < LIR < ∼10 L⊙) and 34 normal spiral galaxies with lower IR ...

Results are presented for [C ii] 158μm line fluxes observed with the Herschel PACS instrument in 112 sources with both starburst and active galactic nucleus (AGN) classifications, of which 102 sources have confident detections. Results are compared with mid-infrared spectra from the Spitzer Infrared Spectrometer and with Lir from IRAS fluxes; AGN/starburst classifications are determined from eq...