Abstract BACKGROUND Macrophages can cross blood-brain-barrier (BBB) and infiltrate brain parenchyma with malignancies such as glioma. Recently, many efforts have been made to develop macrophage-based cancer therapy, including CAR–macrophages. However, lack of proliferation in differentiated macrophages hinders their utility. We sought ameliorate this problem by immortalizing assist potential th...

We construct a new efficient algorithm for finding Gröbner–Shirshov bases for noncommutative algebras and their representations. This algorithm uses the Macaulay matrix [F.S. Macaulay, On some formula in elimination, Proc. London Math. Soc. 33 (1) (1902) 3–27], and can be viewed as a representation theoretic analogue of the F4 algorithm developed by J.C. Faugère. We work out some examples of un...

Isolation of azalomycins F3, F4 and Fg from azalomycin F-complex crystals was successfully conducted. F3 was less soluble in methanol than other components and was isolated by fractional crystallization of F-complex from 80~ 100% methanol in water. F4 and F5 were separated by P-cellulose column chromatography, from which F5 and F4 were eluted with 60 % aqueous methanol and 0.01M ammonium acetat...

Trivium is a bit-based stream cipher in the final portfolio of the eSTREAM project. In this paper, we apply the approach of Berbain et al. to Trivium-like ciphers and perform new algebraic analyses on them, namely Trivium and its reduced versions: Trivium-N , Bivium-A and Bivium-B. In doing so, we answer an open question in the literature. We demonstrate a new algebraic attack on Bivium-A. This...

We introduce a class of formally self-dual additive codes over F4 as a natural analogue of binary formally self-dual codes, which is missing in the study of additive codes over F4. We define extremal formally self-dual additive codes over F4 and classify all such codes. Interestingly, we find exactly three formally self-dual additive (7, 27) odd codes over F4 with minimum distance d = 4, a bett...

Concentrations and speciation of Pb, Cu, Cr, Cd, As, Ni in sediment from New Calabar River, Nigeria were assayed. the trace metals determined using UNICAM solar 969 AAS. Speciation was done five steps sequential extractions. Results revealed that for wet dry seasons, concentrations (mg/kg) ranged 1.1E-2±1.0E-3 As to 5.17±0.04 majority bound residual fraction (F5), while Cu mostly exchangeable (...

We have defined the expression of the macrophages (m phi)-specific antigen (Ag) F4/80 during differentiation in culture. The progenitor cells-the colony-forming unit in culture and cluster-forming cell-lacked Ag F4/80 but gave rise to colonies of F4/80-positive adherent m phi, as shown by fluorescence-activated cell sorting and clonal assays with L cell-conditioned medium as the source of growt...

The goal of this study was to isolate and characterize phages that might be used in prevention and treatment of porcine post-weaning diarrhea due to O149 enterotoxigenic E. coli (ETEC). Serotype O149:H10:F4 was especially targeted because this is the dominant ETEC serotype. Mixtures of 10 strains of O149:H10:F4 ETEC and of 10 O149:H43:F4 ETEC were used as hosts for isolation of phages in sewage...