Erythropoietin receptor (EpoR) dimerization is an important step in erythrocyte formation. Its transmembrane domain (TMD) and juxtamembrane (JM) region are essential for signal transduction across the membrane. A construct compassing residues S212-P259 and containing the TMD and JM region of the human EpoR was purified and reconstituted in detergent micelles. The solution structure of the const...

In 1994, Ericsson Mobile Communications launched an initiative to study low-power, low-cost radio interfaces between mobile phones and their accessories. A radio-access solution was sought because it would eliminate the need for cables and overcome lineof-sight restrictions. It was also recognized that a low-cost solution would usher in wireless connectivity for a multitude of new applications ...

Vazirani and the author [Electron. J. Combin., 15 (1) (2008), R130] gave a new interpretation of what we called l-partitions, also known as (l, 0)-Carter partitions. The primary interpretation of such a partition λ is that it corresponds to a Specht module S which remains irreducible over the finite Hecke algebra Hn(q) when q is specialized to a primitive l root of unity. To accomplish this we ...

Genotype main effect and genotype by environment interaction biplot analysis is the best fit model for which-won-where pattern analysis, genotype, test evaluation. Hence, aim of this study was to identify stable high-yielding soybean genotypes production in diverse environments using stability model. Eighteen were evaluated across six during 2019 cropping season a randomized complete block desi...

Previous studies in the mammalian proximal tubule have suggested that para-aminohippurate (PAH) secretion is approximately threefold greater in the straight segment, or pars recta, than in the convoluted segment, or pars convoluta. However, the possibility that the site of maximal PAH secretion might be related better to particular tubule segments as identified by cell type had not been explore...

At the final step of homologous recombination, Holliday junction-containing joint molecules (JMs) are resolved to form crossover or noncrossover products. The enzymes responsible for JM resolution in vivo remain uncertain, but three distinct endonucleases capable of resolving JMs in vitro have been identified: Mus81-Mms4(EME1), Slx1-Slx4(BTBD12), and Yen1(GEN1). Using physical monitoring of rec...

OBJECTIVES Sarcopenia increases falls and fracture risk. Sarcopenia clinical trials require robust quantitative tools to evaluate muscle function; jumping mechanography (JM) is likely one such tool. However, US data comparing JM with traditional tests across the lifespan is limited. This study evaluated the effect of age and sex on JM compared with traditional function tests and lean mass. ME...

Mucus thickness is suggested to be related to mucosal protection. We therefore investigated the importance of the removable mucous layer and epithelial bicarbonate transport in preservation of the gastric juxtamucosal pH (pH(jm)) during luminal acid. Anesthetized rats were prepared for intravital microscopy of the gastric mucosa, and pH(jm) was measured with pH-sensitive microelectrodes. The mu...