Protein-mediated "chromosome kissing" between two DNA sites in trans (or in cis) is known to facilitate three-dimensional control of gene expression and DNA replication. However, the mechanisms of regulation of the long-range interactions are unknown. Here, we show that the replication terminator protein Fob1 of Saccharomyces cerevisiae promoted chromosome kissing that initiated rDNA recombinat...

Kissing bugs (Triatoma spp.) frequently enter homes and bite human and pet occupants. Bites may lead to severe allergic reactions and, in some cases, death. Kissing bugs are also vectors of Trypanosoma cruzi, the cause of Chagas disease. In general, modern houses in the United States are not conducive to domiciliation of kissing bugs (bugs living out their entire life within the home with the p...

Abstract The presence of kissing bonds (zero-thickness disbond) along the interface an adhesive bond is highly detrimental to its strength and longevity. detection these kind defects has previously been attempted using several techniques such as ultrasonic, infrared thermography, X-ray spectroscopy, etc. This study aims assess effectiveness pencil lead break (PLB) tests a source in detecting di...

Kissing bonds are adhesive bonding defects and are thought to arise from either contamination of the surfaces during manufacture or various forms of environmental attack. . When adhesives are used for safety critical applications the current method is to undertake extremely careful process control. None-the-less premature failure of adhesive joints still occurs and kissing bonds are often the m...

By using optical tweezers, we have investigated the mechanical unfolding of a minimal kissing complex with only two G.C base pairs. The loop-loop interaction is exceptionally stable; it is disrupted at forces ranging from 7 to 30 pN, as compared with 14-20 pN for unfolding hairpins of 7 and 11 bp. By monitoring unfolding/folding trajectories of single molecules, we resolved the intermediates, m...

Kissing nevus is a curious type of nevus that was first described on the eyelids and rarely described on the penis. We report two cases of kissing nevus of the penis and review previously reported cases. The lesions of the kissing nevus of the penis showed characteristic mirror-image symmetry relative to the coronal sulcus. On histopathology, the lesion showed a compound nevus.