BACKGROUND Therapeutic strategies that induce effective neuroprotection and enhance intrinsic repair mechanisms are central goals for future treatment of multiple sclerosis (MS), as well as other diseases. Laquinimod (LQ) is an orally administered, central nervous system (CNS)-active immunomodulator with demonstrated efficacy in MS clinical trials and a favorable safety and tolerability profile...

AIM To evaluate and compare the functional status in surgically treated patients with Carpal tunnel syndrome (CTS) compared with those treated conservatively by Levine Questionnaire (LQ) in relation to electroneurographic findings. METHODS The prospective study included 80 patients with diagnosed CTS. Patients were assessed clinically and electrophysiologically. The main outcome measures were...

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BACKGROUND Cervical cancer is caused by high-risk types of human papillomavirus (HPV). DNA testing of such high-risk types of HPV could improve cervical screening.The aim of the study was to compare the sensitivities and positive predictive values of two commercially available typing assays (Qiagen LQ and Roche LA) and to comparatively assess the distribution of HPV types with these two assays....

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G. BIRKHOFF and J . v . NEUMANN1 have shown in 1936 that the closed linear manifolds (subspaces) of the Hilbert space form a complete atomic and ortho-complemented lattice LQ which at least for finite dimensional subspaces is also modular. JAUCH 2 ' 3 , PIRON4 and KAMBER5 have pointed out, that instead of the modularity a weeker condition can be formulated in LQ which is always fulfilled for th...

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We consider a class of `0-regularized linearquadratic (LQ) optimal control problems. This class of problems is obtained by augmenting a penalizing sparsity measure to the cost objective of the standard linear-quadratic regulator (LQR) problem in order to promote sparsity pattern of the state feedback controller. This class of problems is generally NP hard and computationally intractable. First,...

Cocaine, as an indirect dopamine agonist, induces selective behavioral and physiological events such as hyperlocomotion and dopamine release. These changes are considered as consequences of cocaine-induced molecular adaptation such as CREB and c-Fos. Recently, methanolic extracts from licorice was reported to decrease cocaine-induced dopamine release and c-Fos expression in the nucleus accumben...