A patient with symptomatic primary cryoThis case constitutes, to our knowledge, globulinemia was followed for 9 yr and was the first example of amyloidosis associated found at autopsy to have generalized amylwith monoclonal lgG cryoglobulinemia, with oidosis. There was a monoclonal serum characterization of the monoclonal serum protein spike of lgG kappa type that was cryoglobulin, and also the...

A simple method is described for quantitative determination of lgG, IgA, 1gM, a2M, and other proteins without dilution of the sample. Strips of gelatinized cellulose acetate spread with antiserum are used as a supporting medium. The method is accurate, highly reproducible, and seems particularly suitable for routine work because it permits determination of hypo-, normal, and hyperglobulinemia o...

Oral feeding of 50% EtOH extract of Curcuma longa to male rats at the dose of 1gm/kg body weight caused significant reduction of serum cholesterol, triglycerides and phospholipids (P≤0.01 to 0.001). Whereas the SGOT levels aware not reduced significantly. Fertility test showed 80% negative result. The negative fertility results reflects the arrest of spermatogenesis and depletion of androgen le...

To determine it cell membrane phenotypes change under the selective pressures of therapy we have conducted a prospective study of 54 children with lymphoid malignancies of T-like, B-like, common, and null cell types. Membrane phenotypes were determined at diagnosis in all patients and again 1-24 mo later in 18 children who either failed induction therapy or had one or more relapses. In 7 patien...

Antibodies specifically reacting with platelets only in the presence of EDTA. by the platelet immunofluorescence test. were found in the serum of 20 patients with pseudothrombocytopenia due to in vitro EDTA-dependent platelet agglutination. These antibodies reacted optimally at 0-4’C. In 1 9 patients. IgG antibodies were detected; in 8 patients. 1gM or IgA antibodies were also found. In one pat...

Forty patients with Waldenstr#{246}m’s macroglobulinemia were evaluated for criteria of diagnosis, clinical presentation and course. response to therapy, and appropriateness of the classification primary or secondary. A wide spectrum of presentations, course, and complications were present. Thus, the major criteria for diagnosis was a monoclonal 1gM serum protein abnormality present in concentr...