BACKGROUND Senkyunolide I (SEI) is one of the most important bioactive phthalides of Ligusticum chuanxiong Hort. (Umbelliferae), a Traditional Chinese Medicine. Our previous studies suggested that it might be developed as a potential treatment for migraine. METHODS In this paper, we aimed to isolate and characterize the main metabolites of SEI after gavage feeding in rats. Their structures we...

We report the first direct experimental evidence of the dynamic behavior of the solid-electrolyte-interphase (SEI) on copper electrodes upon electrochemical cycling. Synchrotron-based soft X-ray absorption spectroscopy (sXAS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS) consistently show that both the chemical composition and the thickness of the SEI change with electrochemical...

During a 2 day period in mid-September 2006, more than 200, unconfirmed but identifiable, sei whale (Balaenoptera borealis) calls were collected as incidental data during a multidisciplinary oceanography and acoustics experiment on the shelf off New Jersey. Using a combined vertical and horizontal acoustic receiving array, sei whale movements were tracked over long distances (up to tens of kilo...

The Software Engineering Institute (SEI), located in Pittsburgh, Pennsylvania, is a federally funded research and development center operated by Carnegie Mellon University under contract to the Department of Defense. An SEI objective is to provide leadership in software engineering and in the transition of new software engineering technology into practice. This paper discusses a software proces...

This article addresses the issue of the English-only movement in the United States public schools, specifically the Structured English Immersion (SEI) methodology. It discusses the controversy surrounding bilingual education by reviewing theoretical and empirical research about the implementation of SEI. The article articulates that SEI is an appropriate alternative to other bilingual instructi...

BACKGROUND The linkage between the socio-economic inequality and HIV outcomes was analysed using data from a population-based household survey that employed multistage-stratified sampling. The goal is to help refocus attention on how HIV is linked to inequalities. METHODS A socio-economic index (SEI) score, derived using Multiple Correspondence Analysis of measures of ownership of durable ass...

BACKGROUND To survey cancer patients who consume an extract of the Basidiomycetes Agaricus blazei Murill mushroom (Sen-Sei-Ro) to measure their self-assessment of its effects and to develop an instrument for use in future randomized trials. METHODS We designed, translated and mailed a survey to 2,346 Japanese consumers of Sen-Sei-Ro self-designated as cancer patients. The survey assessed cons...

Although risk management approaches appeared more than one decade ago, there is the evidence of low penetration rate of their techniques in software projects. One of the most widely known methods is the SEI Software Risk Evaluation (SEI-SRE) method. This paper addresses the usage of the SEI-SRE method in a big software development project. The Action-Research effort that we carried out suggests...

We extend a popular approach in SEI modeling by refraining from using a single reaction interface. Instead we trace the time evolution of the SEI volume fraction in a spatially resolved way. In this study, we test how neutral lithium interstitial diffusion can explain the continuous growth of the SEI. We observe that transport of neutral lithium interstitials, as estimated by DFT calculation, i...