BACKGROUND Candida represents the most common cause of invasive fungal disease, and candidal blood stream infections (CBSI) are prevalent in the ICU. Inappropriate antifungal therapy (IAT) is known to increase a patient's risk for death. We hypothesized that in an ICU cohort it would also adversely affect resource utilization. METHODS We retrospectively identified all patients with candidemia...

Previous studies in Penicillium chrysogenum and Aspergillus nidulans suggested that self-processing of the isopenicillin N acyltransferase (IAT) is an important differential factor in these fungi. Expression of a mutant penDE(C103S) gene in P. chrysogenum gave rise to an unprocessed inactive variant of IAT (IAT(C103S)) located inside peroxisomes, which indicates that transport of the proIAT ins...

Herein, the effect of shortening intercritical annealing (IA) time in a two-step process “intercritical and tempering (IAT)” on microstructure mechanical properties medium-manganese steel (MMnS) made Fe–0.05C–7Mn–1.5Cu–1.5Ni–1.5Al–1.5Si–0.5Mo (wt%) containing copper-rich (CRP) Ni(Al/Mn) precipitates is investigated. The atom probe tomography (APT), electron backscattering diffraction (EBSD), sy...

In two experiments, the use of a self-other Implicit Association Test (IAT) as a measure of implicit self-esteem was examined. In Study 1, participants completed two self-other IATs: one in which the other was unspecified and one in which the other was specified to be a close friend. Esteem-IAT scores were significantly higher for the unspecified other-IAT (d = .82), indicating that the content...

The main goal of the present study is to investigate the psychometric properties of a French version of the Internet Addiction Test (IAT) and to assess its relationship with both time spent on Internet and online gaming. The French version of the Young's Internet Addiction Test (IAT) was administered to a sample of 246 adults. Exploratory and confirmatory analyses were carried out. We discovere...

Copy Abstract: The present work analyses the predictive validity of measures provided by several available self-report and indirect measurement instruments to assess risk propensity (RP) and proposes a measurement instrument using the Implicit Association Test: the IAT of Risk Propensity Self-Concept (IAT-RPSC), an adaptation of the prior IAT-RP of Dislich et al. Study 1 analysed the relationsh...

Two studies investigated the use of the Implicit Association Test (IAT; A. G. Greenwald, D. E. McGhee, & J. L. K. Schwartz, 1998) to study age differences in implicit social cognitions. Study I collected IAT (implicit) and explicit (self-report) measures of age attitudes, age identity, and self-esteem from young, young-old, and old-old participants. Study 2 collected IAT and explicit measures o...

Drawing on recent criticism of the Implicit Association Test (IAT), the present study tested the convergent and discriminant validity of two prejudice-related IATs to corresponding explicit prejudice measures in a German student sample (N = 61). Confirming convergent validity, (a) an IAT designed to assess negative associations related to Turkish people was significantly related to the explicit...

The Implicit Association Test (IAT) was adapted to measure anxiety by assessing associations of self (vs. other) with anxiety-related (vs. calmness-related) words. Study 1 showed that the IAT-Anxiety exhibited good internal consistency and adequate stability. Study 2 revealed that the IAT-Anxiety was unaffected by a faking instruction. Study 3 examined the predictive validity of implicit and ex...

With the development of the Internet, an increasing number of adolescents play online game excessively, which leads to adverse effects on individuals and society. Previous studies have demonstrated altered gray-matter volume (GMV) in individuals with Internet gaming disorder (IGD), but the relationship between the tendency to IGD and the GMV across whole brain is still unclear in adolescents. I...