نتایج جستجو برای: سیستم dims

تعداد نتایج: 74455  

2015
Alexander A. Goldberg Hossam Draz Diana Montes-Grajales Jesus Olivero-Verbél Stephen H. Safe J. Thomas Sanderson

We recently reported that novel ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells. In this paper, we have focused on the mechanism(s) associated with ring-DIM-mediated cell death, and on identifying the specific intracellular target(s) of these compounds. The 4,4'- and 7,7'-dichloroDIMs and 4,...

Journal: :The Journal of biological chemistry 2001
L R Camacho P Constant C Raynaud M A Laneelle J A Triccas B Gicquel M Daffe C Guilhot

Among the few characterized genes that have products involved in the pathogenicity of Mycobacterium tuberculosis, the etiological agent of tuberculosis, are those of the phthiocerol dimycocerosate (DIM) locus. Genes involved in biosynthesis of these compounds are grouped on a 50-kilobase fragment of the chromosome containing 13 genes. Analysis of mRNA produced from this 50-kilobase fragment in ...

Journal: :Int. J. Hum. Comput. Interaction 2003
Sun-Kai V. Lin Eric J. Seibel Thomas A. Furness

For the goal of designing a wearable low vision aid, aspects of both head-mounted display (HMD) design and performance evaluation were integrated into a single study of scanning ability. A head-mounted version of a novel retinal light scanning display known as the virtual retinal display was fabricated for this study. A remote head CCD (charge coupled device) attached approximately at the user’...

Journal: :Plant physiology 2016
Jean-Luc Cacas Corinne Buré Kevin Grosjean Patricia Gerbeau-Pissot Jeannine Lherminier Yoann Rombouts Emmanuel Maes Claire Bossard Julien Gronnier Fabienne Furt Laetitia Fouillen Véronique Germain Emmanuelle Bayer Stéphanie Cluzet Franck Robert Jean-Marie Schmitter Magali Deleu Laurence Lins Françoise Simon-Plas Sébastien Mongrand

The lipid composition of plasma membrane (PM) and the corresponding detergent-insoluble membrane (DIM) fraction were analyzed with a specific focus on highly polar sphingolipids, so-called glycosyl inositol phosphorylceramides (GIPCs). Using tobacco (Nicotiana tabacum) 'Bright Yellow 2' cell suspension and leaves, evidence is provided that GIPCs represent up to 40 mol % of the PM lipids. Compar...

2014
Jennifer A Kirwan Ralf J M Weber David I Broadhurst Mark R Viant

Direct-infusion mass spectrometry (DIMS) metabolomics is an important approach for characterising molecular responses of organisms to disease, drugs and the environment. Increasingly large-scale metabolomics studies are being conducted, necessitating improvements in both bioanalytical and computational workflows to maintain data quality. This dataset represents a systematic evaluation of the re...

Journal: :Lebensmittel-Wissenschaft & Technologie 2022

Volatile fingerprinting by Headspace-Solid-Phase Microextraction followed Direct Injection Mass Spectrometry (HS-SPME DIMS) has been assessed for the first time as an alternative approach to gas chromatographic methods GC-MS) rapid classification of honey botanical origin. In order fully evaluate potential SPME authentication, samples from different sources (eucalyptus, citrus, acacia, rosemary...

Journal: :International Journal of Molecular Sciences 2021

Flavonoids represent an important class of secondary metabolites because their potential health benefits and functions in plants. We propose a novel method for the comprehensive flavonoid filtering screening based on direct infusion mass spectrometry (DIMS) analysis. The recently invented data mining procedure, multi-step mass-remainder analysis (M-MARA) technique is applied effective spectral ...

Journal: : 2022

در این مقاله یک مدل ریاضی برای مسئله سیستم تولیدی همکارانه ساخت بر اساس سفارش با رعایت انصاف تخصیص بار‌های تولید طراحی شده است. اهداف اصلی مدل، کمینه‌سازی هزینه‌‌های کل و حداکثر استفاده از منابع به‌منظور عادلانه شرایط عدم­قطعیت کنترل پارامتر‌های غیرقطعی روش برنامه‌ریزی فازی ‌شده نتایج نشان می‌دهد افزایش نرخ عدم‌قطعیت، می­یابد. ازآنجاکه ظرفیت کارخانه‌ها ثابت است، مقدار تقاضا، هر کارخانه نیز می­ی...

2015
Sean L. Seyler Avishek Kumar M. F. Thorpe Oliver Beckstein

Diverse classes of proteins function through large-scale conformational changes and various sophisticated computational algorithms have been proposed to enhance sampling of these macromolecular transition paths. Because such paths are curves in a high-dimensional space, it has been difficult to quantitatively compare multiple paths, a necessary prerequisite to, for instance, assess the quality ...

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