Vancouver, October 2005. Bridging the Gap between Technology and Users: Leveraging Machine Translation in a Visual Data Triage Tool Thomas Hoeft Nick Cramer M. L. Gregory Elizabeth Hetzler Pacific Northwest National Laboratory Pacific Northwest National Laboratory Pacific Northwest National Laboratory Pacific Northwest National Laboratory 902 Battelle Blvd. 902 Battelle Blvd. 902 Battelle Blvd....

The prediction of human drug metabolites using in vitro experiments containing human-derived reagents is an important approach in modern drug research; however, this can be challenging for drugs that are slowly metabolized. In this report, we describe the use of a recently developed human hepatocyte relay method for the purpose of predicting human drug metabolite profiles. Five compounds for wh...

Point mutations in the humanMYO1E gene, encoding class I myosin Myo1e, are associated with focal segmental glomerulosclerosis (FSGS), a primary kidney disorder that leads to end-stage kidney disease. In this study, we used a simple model organism, fission yeast Schizosaccharomyces pombe, to test the effects of FSGSassociated mutations on myosin activity. Fission yeast has only one class I myosi...

The prevalence of diabetes is increasing worldwide with the trend of patients being young and creating a significant burden on health systems, including reproductiveproblems,but theeffectsofdiabeteson embryo implantation are still poorly understood. Our study was to examine effects of diabetes on mouse embryo implantation, providing experimental basis for treating diabetes and its complications...

In this work, the electrocatalytic oxidation of ethanol was studied in acidic media at the wholly electrosynthesized nanocomposites: platinum and its alloys (copper and nickel) anoparticles/reduced graphene oxide on the carbon-ceramic electrode (Pt/rGO/CCE, Pt-Cu/rGO/CCE, and Pt-Ni/rGO/CCE electrocatalysts). The electrosynthesized nanocomposites were characterized by scan...

Addressed herein, functionalized multi-walled carbon nanotube (MWCNT) supported highly monodisperse nickel nanoparticles modified on glassy carbon electrode (Ni@f-MWCNT/GCE) were synthesized through microwave assisted method and examined for non-enzymatic glucose sensing in ionic liquids by cyclic voltammetry and chronoamperometry. The results of Ni@f-MWCNT/GCE electrode were compared with Ni N...

In order to determine whether the central organismic variable of stimulus trace theory, i.e., neural integrity (ni), was more closely related to MA or IQ, comparisons were made between digit span performance of groups who were matched on either MA or CA but who differed in IQ. Differences were found between normal, borderline, and retarded IQ groups matched on CA, but not between those matched ...