نتایج جستجو برای: رنیم 186
تعداد نتایج: 8926 فیلتر نتایج به سال:
چکیده در ایـن پـروژه دو کمپلکس تک هسته ای re(v) با فـرمـول هـای [reo(ome)(pph3)2 (alizarin)2] و [reo(ome)2(pph3)2 (alizarin)] سنتز شدند، که در آنها alizarin، 3-((3-نیتروفنیل)هیدرازینیل دی ان)-6-اکسیدانیلیدین-سیکلوهگزا-1و4-دی ان-1-کربوکسیلات می-باشد. کمپلکس های سنتز شده روش های ft-ir ، uv-vis و آنالیز عنصری شناسایی شدند. ساختار این کمپلکس ها توسط نرم افزار گوسین، نسخه 9 و به روش نیمه تجربی pm6...
OBJECTIVE Rhenium is one of the most valuable elements for internal radiotherapy because (186)Re and (188)Re have favorable physical characteristics. However, there are problems when proteins such as antibodies are used as carriers of (186/188)Re. Labeling methods that use bifunctional chelating agents such as MAG3 require the conjugation of the (186/188)Re complex to protein after radiolabelin...
Prostate cancer is one of the leading causes of cancer deaths among men, many miRNAs have been demonstrated to play critical role in the progression of prostate cancer, miR-186 suppresses the progression of many tumors, such as bladder cancer and glioma. Previous study shows miR-186 is downregulated in prostate cancer tissues, and is a good prognosis for prostate cancer patients. In this study,...
The pharmacokinetics of 186Re-HEDP, a radiopharmaceutical for palliative treatment of metastatic bone pain, was investigated in 11 patients (17 studies) who suffered from metastatic breast or prostate cancer. Half-life times of 186Re in three blood fractions (whole blood, plasma and plasma water) were 40.1 +/- 5.0, 41.0 +/- 6.0 and 29.5 +/- 6.4 hr, respectively. Time-dependent increase in plasm...
Relapsed/refractory multiple myeloma represents a major challenge in multiple myeloma therapy. For patients with relapsed/refractory multiple myeloma, we developed a treatment schema of metronomically scheduled drug therapy. We identified 186 patients who had been treated with metronomic therapy between March 2004 and January 2012 with a median follow up of 24.2 months. Median age was 61 years ...
Background: To investigate the role of miR-186 in the carcinogenesis and metastasis of human urothelial bladder cancer and its potential target protein. Methods: Quantitative real-time PCR (qRT-PCR) was performed to detect miR-186 expression in human urothelial bladder cancer tissues and cell lines. Then, Bioinformatics analysis, combined with luciferase reporter assay demonstrated the miR-186’...
BACKGROUND Increasing evidence has shown that microRNAs function as oncogenes or tumor suppressors in human malignancies, but the roles of miR-186 in human bladder cancer (BC) is still unclear. METHODS First, quantitative real-time PCR (qRT-PCR) was performed to detect miR-186 expression in bladder cancer tissues and cell lines. Then, Bioinformatics analysis, combined with luciferase reporter...
در این تحقیق تعدادی از کمپلکس های رنیم (i)- تری کربونیل با فرمول کلی [re(co)3(nn)cl]، سنتز و به کمک آنالیز عنصری و روش های مختلف طیف سنجیft-ir، 1h-nmr، 13c-nmr، massو uv-vis شناسایی شدند. ساختار بلوری برخی کمپلکس های سنتز شده بوسیله پراش پرتو x به روش تک بلور مشخص گردید. لیگاندهای دودندانه (nn) ایمینی از طریق واکنش تراکمی بین اتیلن دی آمین و برخی از مشتقات بنزآلدهید با یک یا دو اتم یا گروه استخ...
Previous studies have shown that microRNA-186 (miR-186) is overexpressed in various human cancers and is associated with the regulation of the carcinogenic processes. However, the underlying mechanisms of this microRNA in melanoma remain largely unknown. In the present study, the overexpression of miR-186 was identified in melanoma tissues and melanoma cells compared to the expression of miR-18...
Recent evidence shows that miRNAs are dysregulated in a variety of cancers including gastric cancer (GC), and emerging as key oncogenes or tumor suppressors. In this study, qRT-PCR was used to analyze the expression of miR-186 in GC tissues and adjacent non-cancerous tissues, and then more in-vitro experiments were used to investigate the role of miR-186 in GC cells. Here, we identified miR-186...
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