Cultural and environmental factors interact in determining the genetic structure of human populations. Bio-demographic investigations of ethnic minorities are able to disentangle the influences that these two components have on the evolution of the genetic structure of a population. The ethnic minority of the Arbëreshe of the province of Cosenza (Calabria, southern Italy) is analyzed in this pa...

BACKGROUND Glucose-6-phosphate dehydrogenase is one of the most common genetic deficiencies, which approximately 400 million people in the world suffer from. According to authors' initial search, numerous studies have been carried out in Iran regarding molecular variants of this enzyme. Thus, this meta-analysis presented a reliable estimation about prevalence of different types of molecular mut...

We report a case of a chronic myeloid leukemia patient showing progressive bone marrow fibrosis and anemia during imatinib therapy. Given the loss of major molecular response, we switched treatment to dasatinib 100 mg daily, observing a reduction in BCR-ABL transcript, a significant improvement of anemia, and a gradual disappearance of fibrosis. After 7 years of dasatinib therapy the patient ma...

1Department of Cardiovascular and Thoracic Sciences, Clinica Medica 2 and 2Department of Clinical and Experimental Medicine, Group of Clinical Epidemiology, University of Padua, Padua, Italy; 3Department of Internal Medicine and Angiology, University Hospital of Parma, Parma, Italy; 4Department of Internal Medicine, Civic Hospital of Cosenza, Cosenza, Italy; 5Department of Angiology and Blood C...

We report a case of a chronic myeloid leukemia patient showing progressive bone marrow fibrosis and anemia during imatinib therapy. Given the loss of major molecular response, we switched treatment to dasatinib 100 mg daily, observing a reduction in BCR-ABL transcript, a significant improvement of anemia, and a gradual disappearance of fibrosis. After 7 years of dasatinib therapy the patient ma...

We report a case of a chronic myeloid leukemia patient showing progressive bone marrow fibrosis and anemia during imatinib therapy. Given the loss of major molecular response, we switched treatment to dasatinib 100 mg daily, observing a reduction in BCR-ABL transcript, a significant improvement of anemia, and a gradual disappearance of fibrosis. After 7 years of dasatinib therapy the patient ma...

1Section of Microbiology, Department of Experimental and Applied Medicine, and 2Section of General Pathology, Department of Biomedical Sciences and Biotechnology, School of Medicine, University of Brescia, Brescia, Italy; 3Department of Pharmaco-Biology, University of Calabria, Arcavacata di Rende (Cosenza), Italy; and 4 Department of Pathology, School of Medicine, University of Brescia, Bresci...

A bstract . This pap er concern s the study of some mathemati cal proper t ies of Thermodyn amic Au tomata . In the pr esen t pap er , t he govern ing lineari zed differenti al equat ionsfor which a rigorous trea tment is po ssibl eare studied . The driving terms are assumed period ic and t he controls are assumed piecewise const ant . T he explicit solut ion is found in the most general case w...

L Malaguarnera, J Simporè, DA Prodi, A Angius, A Sassu, I Persico, R Barone and S Musumeci Department of Biomedical Sciences, University of Catania, Italy; Centre Medical San Camille, Ouagdougou, Burkina Faso, Italy; Institute of Population Genetics, CNR, Alghero, Italy; Institute of Neurological Sciences, Catania Section, CNR, Cosenza, Italy; Department of Pharmacology, Gynecology/Obstetrics, ...

The article reconstructs the history of Scuola Normale Cosenza from its birth, after constitution Kingdom Italy, until eve Great War. In more than half a century School, despite logistical, economic and organizational difficulties, has played an important role in training teachers who have contributed to dissemination education growth, not free contradictions limits, Calabrian Southern society.