OBJECTIVE The N-methyl-D-aspartic acid (NMDA) class of glutamate receptors has received attention in the pathophysiology of schizophrenia because of the similarity between some schizophrenic symptoms and symptoms caused by NMDA antagonists. To determine if NMDA receptor abnormalities were present at the mRNA level, expression of NMDA receptor (NR) subunits NR(1), NR(2A), and NR(2B) was measured...

In many European countries, the deregulation of energy markets leading to the introduction of unbundling and incentive regulation for utilities firms has made the task of setting an adequate cost of equity more difficult. Firstly, Legal Unbundling led to the creation of many legally independent network operators that have to be regulated separately, excluding the generation or sales activities ...

Gerade erst wurde das Urlaubsgeld gestrichen und das Weihnachtsgeld gekürzt, kurz darauf wird die Arbeitszeit verlängert – ohne Lohnausgleich. Kein Wunder, dass die Angestellten im Öffentlichen Dienst aufgebracht sind. Als spontane Reaktion auf den Beschluss der Bundesländer zur Arbeitszeitverlängerung hatte es bereits Ende März erste Proteste gegeben. Nun liegen sogar Warnstreiks in der Luft –...

Nr-CAM, a cell-cell adhesion molecule of the immunoglobulin-like cell adhesion molecule family, known for its function in neuronal outgrowth and guidance, was recently identified as a target gene of beta-catenin signaling in human melanoma and colon carcinoma cells and tissue. Retrovirally mediated transduction of Nr-CAM into fibroblasts induces cell motility and tumorigenesis. We investigated ...

Even though hearing aid (HA) users can respond very differently to noise reduction (NR) processing, knowledge about possible drivers of this variability (and thus ways of addressing it in HA fittings) is sparse. The current study investigated differences in preferred NR strength among HA users. Participants were groups of experienced users with clear preferences ("NR lovers"; N = 14) or dislike...

Nitrate reductase (NR) is rapidly inactivated by phosphorylation of serine residues in response to loss of light or reduction in COz levels. To identify sites within NR protein that play a role in this post-translational regulation, a heterologous expression system and an in vitro inactivation assay for Arabidopsis NR were developed. Protein extracts containing NR kinases and inhibitor proteins...

NR is a point and click GUI interface for browsing Usenet news. The NR interface is built using the Tk interface toolkit, and coded entirely in the Tcl scripting language. NR was designed as a framework for pursuing research into electronic information browsing. As a result, NR had strong requirements for configurability, extensibility, portability, and performance. This paper describes how tho...