In this study, the in vitro antimicrobial activities of four plant essential oils (T. schimperi, E. globulus, R. officinalis, and M. Chamomilla) were evaluated against bacteria and fungi. The studies were carried out using agar diffusion method for screening the most effective essential oils and agar dilution to determine minimum inhibitory concentration of the essential oils. Results of this s...

Chamomile (Matricaria chamomilla L.) is renowned for its production of essential oils, which major components are sesquiterpenoids. As the important enzyme in the sesquiterpenoid biosynthesis pathway, the enzyme 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) catelyzes the first committed step of isoprenoids biosynthesis in MVA pathway. In this study, a full-length cDNA encoding HMGR (designate...

To find new tachykinin NK1 receptor antagonists from natural sources, we examined the tachykinin antagonist activity in the extracts of approximately 200 species of plants by the use of isolated guinea pig ileum. As a result, we discovered a novel and potent NK1 receptor antagonist in the extract of dried flowers of Matricaria chamomilla L. (chamomile). The structure of the antagonist was estab...

BACKGROUND Plants are the natural source of antioxidants as well as antimicrobial compounds that has great potentials in pharmaceutical industry. In the present study, two medicinal plants Atropa belladonna and Matricaria chamomilla were collected from Northern areas of Pakistan. MATERIALS AND METHODS The extracts of the collected plants were obtained by microwave assisted extraction (MAE) wi...

This experimental and dose-response curve study aimed to carry out the quality control of the Chamomilla recutita sample, as well as to estimate the ideal dose, for anti-inflammatory effect, of the extract of its capitula, in patients with phlebitis due to peripheral intravenous infusion of antineoplastic chemotherapy and to evaluate the toxicity of this extract in human beings. The therapeutic...

Matricaria chamomilla contained oils, sterols, triterpenes, flavonoids, saponins, tannins, alkaloids, sugars, proteins, mucins, sesquiterpenes, coumarins, polyacetylenes, phenyl carboxylic acids, amino phytosterols, choline and mineral substances. The pharmacological studies revealed that possessed dermatological, antioxidant, anticancer, anti-inflammatory, analgesic, antimicrobial, reproductiv...

Post-marketing control of Matricaria chamomilla L. and Thymus vulgaris products by reference developed methods