BACKGROUND Surviving myocardial cells near the infarct border zone form the arrhythmogenic substrate for sustained ventricular tachycardia (VT) in humans. Infarct-related artery (IRA) patency may modulate the electrophysiological function of this arrhythmogenic substrate and its response to antiarrhythmic drug therapy. We postulated that effective antiarrhythmic drug therapy selected during ser...

BACKGROUND Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a major contributor to the development of atherosclerotic process. In a previous work, we demonstrated that the insulin receptor isoform A (IRA) and its association with the insulin-like growth factor-I receptor (IGF-IR) confer a proliferative advantage to VSMCs. However, the role of IR and IGF-IR in VSMC...

We lay down plans to study how Inductive Reasoning Ability (IRA) affects the analyzing and understanding of Program Visualization (PV) systems. Current PV systems do not take into account the abilities of the user but show always the same visualization independently of the changing knowledge or abilities of the student. Thus, we propose IRA as an important skill when comprehending animation, wh...

One form of the inclusion-exclusion principle asserts that if A and B are functions of finite sets then the formulas A(S) = ∑ T⊆S B(T ) and B(S) = ∑ T⊆S(−1) |A(T ) are equivalent. If we replace B(S) by (−1)|S|B(S) then these formulas take on the symmetric form A(S) = ∑

We describe here the construction and testing of an IRA with dual polarity. Four feed arms are evenly spaced around the reflector, and each channel consists of a pair of arms on opposite sides of the reflector. Each channel uses a standard balun to convert the 50-ohm input impedance to 200 ohms. Since the characteristic impedance of each channel is 400 ohms, there is a 2:1 impedance mismatch at...

A major debate exists on whether expanding tax-favoured savings accounts such as Individual Retirement Accounts (IRAs) will increase national savings. Much of the empirical debate has centred on whether IRA contributions before the Tax Reform Act of 1986 represented new savings or merely reshuffled assets. We find no evidence that households financed their IRA contributions from reductions in c...

Solar radiation is well known to damage human skin, for example by causing premature skin ageing (i.e. photoageing). We have recently learned that this damage does not result from ultraviolet (UV) radiation alone, but also from longer wavelengths, in particular near-infrared radiation (IRA radiation, 760-1,440 nm). IRA radiation accounts for more than one third of the solar energy that reaches ...

Innate response activator (IRA) B cells are a subset of B-1a derived B cells that produce the growth factors granulocyte macrophage colony stimulating factor and IL-3. In mouse models of sepsis and pneumonia, B-1a B cells residing in serosal sites recognize bacteria, migrate to the spleen or lung, and differentiate to IRA B cells that then contribute to the host response by amplifying inflammat...