 T. O. White, FRCSEd(Tr&Orth), MD, FFTEd, Consultant Orthopaedic Trauma Surgeon  S. P. Mackenzie, MBChB, BSc MedSci (Hons), MRCS, Specialty Registrar  T. H. Carter, BSc(Hons), MBChB, MRCS(Ed), Specialty Registrar  O. R. Prescott, BSC BMBS PGCert, Foundation Doctor  A. D. Duckworth, BSc(Hons), MBChB, MSc, FRCSEd(Tr&Orth), PhD, Specialty Registrar  J. F. Keating, MPhil, FRCSEd(Tr&Orth), Con...

Background The global increase in acceptance and use of herbal remedies in recent times is still accompanied with poor knowledge of their potential adverse effects and the toxicological implications of their use are underestimated. Methods Bon-santé Cleanser® (BSC), a polyherbal containing Anogeissus leiocarpus, Terminalia ivorensis, Massularia acuminate and Macuna pruriens, is an "energizer ...

We introduce a community detection algorithm (Fluid Communities) based on the idea of fluids interacting in an environment, expanding and contracting as a result of that interaction. Fluid Communities is based on the propagation methodology, which represents the state-of-the-art in terms of computational cost and scalability. While being highly efficient, Fluid Communities is able to find commu...

Forward stair climbing (FSC) is associated with cardiovascular fitness benefits, but the training effects of backward stair climbing (BSC) have not been reported in the literature. This study compared the effects of 8 weeks of FSC and BSC on the cardiovascular parameters of apparently healthy young adults. Forty apparently healthy young adults, aged 18-30 years were recruited consecutively and ...

PURPOSE The prognosis of platinum-based chemotherapy-resistant metastatic urothelial cancer of the bladder remains poor. Personalized selection of the right peptides for each patient could be a novel approach for a cancer vaccine to boost anticancer immunity. EXPERIMENTAL DESIGN In this randomized, open-label, phase II study, patients ages ≥18 years with progressive bladder cancer after first...

A bumetanide-sensitive Na-K-2Cl cotransporter, BSC-1, is believed to mediate the apical component of transcellular NaCl absorption in the thick ascending limb (TAL) of Henle's loop. To study its ultrastructural localization in kidney, we used an affinity-purified, peptide-derived polyclonal antibody against rat BSC-1. Immunoblots from rat kidney cortex and outer medulla revealed a solitary 161-...

We examine the association between contingency variables and the adoption of a Balanced Scorecard (BSC). The contingency variables we examine include business-level strategy, firm size, environmental uncertainty, and investment in intangible assets. Utilizing both survey and archival data, collected as part of a mixed-methodology design, we find that BSC adoption is significantly related to bus...

BACKGROUND After intradural cranial surgery, a dural substitute is often required for dural closure. Although preferred, limitations of autograft include local availability and additional surgical site morbidity. Thus, allografts, xenografts, and synthetics are frequently used. OBJECTIVE To report 6-month results of a randomized, controlled trial of a biosynthesized cellulose (BSC) composed d...

Blood circulating cell-free DNA (cfDNA) is becoming popular in the search of promising predictive and prognostic biomarkers. Among these biomarkers, cfDNA methylation markers have especially gained considerable attention. A significant challenge in the utilization of cfDNA methylation markers is the limited amount of cfDNA available for analyses; reportedly, bisulfite conversion (BSC) reduce cf...

Executive Summary Since Kaplan and Norton introduced the Balanced Scorecard (BSC) in the early 1990s, it has become widely adopted by companies and divisions within companies. The BSC was conceived as way to operationalize a company's vision and strategy. In this regard, it is a management system, or as the originators note, a tool for change within the firm or unit. Not surprisingly, the swift...