conclusions our study demonstrated that tgf-β1 serum levels is higher in osteoporotic postmenopausal females than non-osteoporotic ones, and probably aberrant increase in tgf-β1 in postmenopausal females can result in uncoupled bone resorption and formation, which leads to osteoporosis. background postmenopausal osteoporosis is a major cause of morbidity in postmenopausal females. transforming ...

g l o b a l c o m p e t i t i v e n e s s h a s r e c e n t l y b e c o m e a b i g c h a l l e n g e f o r m a n y c o m p a n i e s a r o u n d t h e w o r l d, w h i c h a r e f o r c e d t o s e e k l o w e r c o s t s a n d h i g h e r q u a l i t y f o r w h a t t h e y p r o d u c e. t h e p r o s p e r i t y o f m a n u f a c t u r i n g f i r m s d e p e n d s o n s e l e c t i n g a n...

o r g a n i z a t i o n s i n a s u p p l y c h a i n a r e i n d e p e n d e n t e n t i t i e s. a l t h o u g h a c o m p l e t e l y i n t e g r a t e d s o l u t i o n m a y r e s u l t i n o p t i m a l s y s t e m p e r f o r m a n c e, s u p p l y c h a i n m e m b e r s a r e i n t e r e s t e d i n o p t i m i z i n g t h e i r o w n o b j e c t i v e r a t h e r t h a n t h a t o f t...

results at high concentrations (40 and 100 μm), apoptosis was demonstrated and it was clearly more prominent in hepatocytes exposed to celecoxib loaded liposomes. conclusions our results showed that celecoxib loaded liposomes robustly induced apoptosis, an action that can potentially make it more relevant than the usual form for chemopreventive strategies and also may raise concerns about its t...

Railway optimization problems have been studied from a mathematical programming perspective for decades. This approach is particularly well suited to model the multitude of constraints that typically arises in the context of a railway system. In recent years, these problems have attracted some attention in the algorithms community, with a focus on individual problem aspects, in an attempt to un...

background: h e r2/ n eu i so n e o ftheepi de rmalg r owth f actor r e c e pt o rsfami l i e s andsee m stohaveprognosticsignificanceofsomesolid t umors.theo b jecti v eof thisstu d yistoevaluatet h epossi b ilityofher2ex p ressioningastricca n cersand the p o s si b le r e lat i o n ship o fh e r2withtumo r ’scli n icopat h o l o gicpara m e te r sa n d a l s oits pr o gno s tic r o l e .   m...