BACKGROUND Na + /Ca 2+ exchanger (NCX) plays a crucial role in pentylenetetrazol-induced convulsion. However, it is unclear whether NCX is critically involved in hyperthermia-induced convulsion. In this study, we examined the potential changes in NCX3 in the hippocampus and cerebrocortex of rats with hyperthermia-induced convulsion. METHODS Twenty-one Sprague Dawley rats were randomly assigne...

background and objectives: febrile convulsion (fc) is the most common seizure disorder in childhood period. some studies have suggested association between seasons and occurrence of fc. this study was designed to determine demographic features, causes and seasonal variations in cases with fc. method: in this descriptive, cross sectional study, 282 children 6- 60 months with fc were admitted to ...

objective this survey evaluates the necessity of biochemical and imaging findings for patients with initial diagnosis of febrile convulsion, and also aims at determining the degree to which results of paraclinical examinations delineate management of patients. materials & methods data of 302 patients referred to mofid children hospital during two years (2005-2006) for febrile convulsions (fc), ...

OBJECTIVE To clarify clinical characteristics of children with febrile convulsions during primary human herpesvirus 6 (HHV-6) infection. SUBJECTS AND METHODS The clinical characteristics of first febrile convulsion were compared between those with and without primary HHV-6 infection in 105 children. HHV-6 infection was verified by culture or acute/convalescent anti-HHV-6 antibody titres. RE...

Three hundred and three children with febrile convulsions were identified in a national birth cohort of 13 135 children followed up from birth to the age of 5 years. Breech delivery (p less than 0.05) was the only significantly associated prenatal or perinatal factor. There were no associations with socioeconomic factors. Excluding the 13 known to be neurologically abnormal before their first f...

Objective: Febrile convulsion in children is age-dependent and genetic predisposition. However, mild electrolyte disturbances are not uncommon such children. This study was to investigate the effect of disturbance on febrile screen for convulsion-related genes. Methods: retrospective cohort included who admitted Pediatric Emergency Department Guangzhou Women Children’s Medical Center due fever ...

Evaluation of magnesium levels in serum and cerebrospinal fluid of patients with febrile convulsion (FC) hospitalized in Bahrami hospital in Tehran in 2010-2011. In the past, decreased levels of magnesium in serum and CSF of patients with FC were reported. The purpose of this study was to identify the possible role of magnesium in febrile seizures in children. Identifying this condition, we may...

Background: Febrile convulsion is one of the most common types of seizure in childhood (9 month to 5 years of age). Its pathogenesis is unknown, so studying its causes is valuable. The purpose of this study was to determine the serum level of magnesium in children with FC (9 months to 5 years of age). Materials and Methods: In this analytical study, serum level of magnesium in 102 children wi...