OBJECTIVES Isolated lung perfusion (ILuP) and selective pulmonary artery perfusion (SPAP) are experimental surgical techniques to deliver high-dose chemotherapy selectively to the lung for the treatment of lung metastases. ILuP with melphalan (MN) has shown to be feasible in clinical studies but can only be used once because it is invasive. SPAP as an endovascular technique can be repeated seve...

a significant portion of manganese (mn) chemical fertilizers applied to calcareous soils is not absorbed by the first crop and may, therefore, affect the growth as well as chemical composition of the subsequent crops, this being called the residual effect of mn, soil tests may be employed to predict such effects. the present experiment was conducted to study the residual effects of manganese su...

Heavy metals may exacerbate metabolic syndrome (MS) but abnormal serum concentrations of bioelements may also co-exist with MS. The primary aim of the study was to assess the relationship of blood heavy metal and bioelement concentrations and MS, in men aged 50-75 years. Heavy metals-lead (Pb), cadmium (Cd), mercury (Hg), arsenic (As), tungsten (W), Macroelements-magnesium (Mg) and calcium (Ca)...

Doses of xenobiotics at or near LD50 may result in substantial hypothermia in mice. Hypothermia has previously been associated with an increase in micronuclei (MN) formation. The present series of investigations examined the potential for phenol to induce hypothermia in mice and its correlation to previously reported MN induction. In order to examine the potential etiology of phenol-induced MN,...

Mg has been considered a promising biomaterial for bone implants. However, the poor corrosion resistance has become its main undesirable property. In this study, both alloying Mn and laser-melting were applied to enhance the Mg corrosion resistance. The corrosion resistance, mechanical properties, and microstructure of rapid laser-melted Mg-xMn (x = 0-3 wt %) alloys were investigated. The alloy...