نتایج جستجو برای: آزمون kmo

تعداد نتایج: 120653  

Journal: :Cell 2011
Daniel Zwilling Shao-Yi Huang Korrapati V. Sathyasaikumar Francesca M. Notarangelo Paolo Guidetti Hui-Qiu Wu Jason Lee Jennifer Truong Yaisa Andrews-Zwilling Eric W. Hsieh Jamie Y. Louie Tiffany Wu Kimberly Scearce-Levie Christina Patrick Anthony Adame Flaviano Giorgini Saliha Moussaoui Grit Laue Arash Rassoulpour Gunnar Flik Yadong Huang Joseph M. Muchowski Eliezer Masliah Robert Schwarcz Paul J. Muchowski

Metabolites in the kynurenine pathway, generated by tryptophan degradation, are thought to play an important role in neurodegenerative disorders, including Alzheimer's and Huntington's diseases. In these disorders, glutamate receptor-mediated excitotoxicity and free radical formation have been correlated with decreased levels of the neuroprotective metabolite kynurenic acid. Here, we describe t...

2017
Ehsan Sargolzaei Mohammad Nikbakht

The present study is conducted among 283 students from University of Zabol to identify the harm and ethical and social issues in the field of information technology and to classify the immoral practices that students are doing in this field. First various important issues in the field of IT in the social and ethical areas are discussed. Then the cases considered as the most commonly used immora...

Journal: :Methods and applications in fluorescence 2017
Kris Wilson Scott P Webster John P Iredale Xiaozhong Zheng Natalie Z Homer Nhan T Pham Manfred Auer Damian J Mole

The assessment of drug-target engagement for determining the efficacy of a compound inside cells remains challenging, particularly for difficult target proteins. Existing techniques are more suited to soluble protein targets. Difficult target proteins include those with challenging in vitro solubility, stability or purification properties that preclude target isolation. Here, we report a novel ...

2017
Fataneh Bakhshi Davoud Shojaeizadeh Roya Sadeghi Saharnaz Nedjat Mohammad Hossein Taghdisi Glenn Laverack

BACKGROUND As the core of health promotion, proper assessment of empowerment is a base for planning for a process that increases people's control on their decisions, lifestyle, and effective activities for their health. OBJECTIVE To design and develop a special tool to assess the empowerment of NGO women in Iran. METHODS This successive exploratory study of combinational type was conducted ...

2012
Miwa Yamamoto

This study aimed to clarify the dilemma of nurses working in general wards who face the ethical dilemma of restraining older people with dementia in Midwestern Japan. The study used the questionnaire method with an independently prepared questionnaire. The questionnaire was designed to ensure privacy and anonymity. The privacy and anonymity of study participants was assured. Of the 340 survey q...

2016
Damian J Mole Scott P Webster Iain Uings Xiaozhong Zheng Margaret Binnie Kris Wilson Jonathan P Hutchinson Olivier Mirguet Ann Walker Benjamin Beaufils Nicolas Ancellin Lionel Trottet Véronique Bénéton Christopher G Mowat Martin Wilkinson Paul Rowland Carl Haslam John P Iredale Damian J. Mole

(2016). Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis. General rights This document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: Explore Bristol Research is a digital archive and the intention is that deposited content shou...

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