We studied the salt taste change during pregnancy and investigated its meaning in normal pregnancy and preeclampsia female in salt restriction. 40 normal pregnant female, 35 pregnant female with preeclampsia and 64 healthy non-pregnant female were recruited to this study. Gustatory test was performed with the filter-paper disk method. Salt solutions, 0.1, 0.2, 0.4, 0.6, 0.8 and 1.0 weight % wer...

PROBLEM Cytomegalovirus (CMV) infection was previously reported in pregnancy complications. However, its seroprevalence and associated Toll-like receptor (TLR) expression in early-onset preeclampsia (EOPE) with hemolysis, elevated liver enzyme and low platelets syndrome (HELLPs) are unexplored. METHOD OF STUDY A case–control study was performed to examine maternal CMV antibodies, neutrophil T...

BACKGROUND: Preeclampsia is hypertension in pregnancy which are characterized by high blood pressure, proteinuria that occur after 20 weeks of GA. remains a massive cause maternal morbidity and mortality 50.000 death annually. The preeclampsia still unclear but there possibility caused immunological processes micro placenta environment during the early age pregnancy. It suggested cytokines such...

Objectives: Preeclampsia is a multisystem disorder which complicates 2-5% of all pregnancies and is the second major cause of maternal mortality. The latest researches indicated that antihypertensive therapy with alphamethyldopa may have an effect on the concentration of placental hormones in pregnancies complicated by preeclampsia. The aim of this study was to determine the effect of α-methyld...

The availability of nitric oxide (NO), which is required for the normal regulation of vascular tone, may be decreased in preeclampsia, thus contributing to the vascular pathogenesis of this pregnancy disorder. Because ascorbate is essential for the decomposition of S-nitrothiols and the release of NO, we speculated that the ascorbate deficiency typical of preeclampsia plasma might result in dec...

background: the physiological changes in thyroid gland during pregnancy have been suggested as one of the pathophysiologic causes of preeclampsia. objective: the aim of this study was comparison of serum levels of tri?iodothyronine (t3), thyroxine (t4), and thyroid?stimulating hormone (tsh) in preeclampsia and normal pregnancy. materials and methods: in this case?control study, 40 normal pregna...

background: previous studies have shown that preeclampsia is associated with elevated maternal serum homocysteine levels, but few studies have evaluated homocysteine levels in amniotic fluid in these patients. the purpose of this study was to compare amniotic fluid homocysteine levels in preeclamptic women, with those of normal pregnant women. methods: a cross sectional study was done on 46 pre...

BACKGROUND First trimester Pregnancy Associated Plasma Protein A (PAPP-A) levels, routinely measured for aneuploidy screening, may predict development of preeclampsia. This study tests the hypothesis that first trimester PAPP-A levels correlate with soluble fms-like tyrosine kinase-1 (sFlt-1) levels, an angiogenic marker associated with preeclampsia, throughout pregnancy. METHODS sFlt-1 level...

abstract background: pregnancy is associated with many physiological changes, which in some cases may cause serious risks such as preeclampsia, and fetal and maternal health threats. recent research has focused on the relationship between metabolic syndrome and preeclampsia. by identifying appropriate indicators for early diagnosis, maternal–fetal complications can be prevented. the present stu...

Systemic inflammation and oxidative stress are features of normal pregnancy and, in excess, contribute to the pathogenesis of preeclampsia. Inflammatory cell activation stimulates uptake of arginine (the precursor for nitric oxide) by transport system y+, expression of one of its genes (CAT-2) together with inducible nitric oxide synthase, leading to nitric oxide production. We investigated whe...