Award Number: W81XWH-08-1-0108 TITLE: The role of eIF4E activity in breast cancer PRINCIPAL INVESTIGATOR: Thomas A Hughes CONTRACTING ORGANIZATION: University of Leeds Leeds LS2 9-0000 REPORT DATE: August 2010 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT:  Approved for public release; distribution ...

3 Abstract Algebra 32 3.1 Binary Operations on Sets . . . . . . . . . . . . . . . . . . . . 32 3.2 Commutative Binary Operations . . . . . . . . . . . . . . . . 32 3.3 Associative Binary Operations . . . . . . . . . . . . . . . . . . 32 3.4 Semigroups . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3.5 The General Associative Law . . . . . . . . . . . . . . . . . . 34 3.6 Identity el...

Fatigue is a recognised problem in the transport industry. It has been attributed to two main influences: time of day and the time since last sleep. While the role of these two influences in producing fatigue is not disputed, there is less agreement on how they interact with one another. The aim of this study was to examine the relative effects of time of day and sleep deprivation on fatigue an...

Prior studies have shown that the IT innovation capability, a company's ability to innovate systematically with IT, is not easily replicated (persistent), and the persistence tends to be more pronounced during periods when economy-wide IT budgets are declining (hard IT budgets), such the post-Y2K period. Building on resource based view we argue that companies that systematically innovate with I...

Award Number: W81XWH-08-1-0108 TITLE: The role of eIF4E activity in breast cancer PRINCIPAL INVESTIGATOR: Thomas A Hughes CONTRACTING ORGANIZATION: University of Leeds Leeds LS2 9-0000 REPORT DATE: August 2010 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT:  Approved for public release; distribution ...

We examine the state of game theory. Many important questions have been answered, and game theoretic methods are now central to much economic investigation. We suggest areas where further advances are important, and argue that models of learning and of social preferences provide promising routes for improving and widening game theory’s predictive power, while preserving the sucesses of existing...

9 Vectors and Quaternions 51 9.1 Vectors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 9.2 Displacement Vectors . . . . . . . . . . . . . . . . . . . . . . . 51 9.3 The Parallelogram Law of Vector Addition . . . . . . . . . . . 52 9.4 The Length of Vectors . . . . . . . . . . . . . . . . . . . . . . 53 9.5 Scalar Multiples of Vectors . . . . . . . . . . . . . . . . . . . . 54...

This reports documents work undertaken in optimising a kinematic model of the human thumb. It is motivated by the high rejection rate observed with myoelectric hand prostheses, which increases with the period of wear and can reach 50% after 5 years. We find that the most commonly-cited reasons for rejecting a prosthesis are its weight, slow actuation speed, and poor durability, whereas the cosm...

2 Sets and Functions 10 2.1 Sets . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 2.2 Unions, Intersections and Complements of Sets . . . . . . . . . 10 2.3 Subsets and Power Sets . . . . . . . . . . . . . . . . . . . . . . 12 2.4 The Specification of Sets . . . . . . . . . . . . . . . . . . . . . 14 2.5 Binary Relations . . . . . . . . . . . . . . . . . . . . . . . . . 15 2.6...

Long term care (LTC) is mainly provided by the family and subsidiarily by the market and the government. To understand the role of these three institutions it is important to understand the motives and the working of family solidarity. In this paper we focus on the case when LTC is provided by children to their dependent parents out of some norm that has been inculcated to them during their chi...