The aqueous extract of Persea americana leaves produced a dose-dependent inhibition of both phases of formalin pain test in mice, a reduction in mouse writhing induced by acetic acid and an elevation of pain threshold in the hot plate test in mice. The extract also produced a dose-dependent inhibition of carrageenan-induced rat paw oedema. The results obtained indicate that the extract possesse...

Cistus ladanifer L. is a medicinal shrub traditionally used against several diseases. The present study was performed for trying to enrich the potentialities of this plant by evaluating possible analgaesic effect aqueous extract Cistus. (AECL) and oral formulation prepared from AECL. tested using acetic acid induces writhing formalin models. results showed that both herbal syrup induced signifi...

pistacia vera l., a member of anacardiaceae family, has been used for sedation and analgesia in traditional medicine. in this study, the antinociceptive and anti-inflammatory effects as well as acute toxicity of the aqueous and ethanolic extracts of p. vera leaves were investigated in mice. the antinociceptive activity was studied using hot plate and writhing tests. the effect of the extracts a...

In this paper, we report the multiwavelength observations of an erupting prominence and associated CME on 13 May 2013. The event occurs behind western limb in field view SDO/AIA. is supported by a highly twisted magnetic flux rope shows rapid rotation counterclockwise direction during rising motion. lasts for $\sim$47 minutes. average period, angular speed, linear speed are $\sim$806 s, $\sim$0...

Amaranthus tricolor Linn. (FamilyAmaranthaceae) popularly known as Joseph’s coat in English. The plant has been used as hepatoprotective and hypoglycemic in Indian system of traditional medicine. In present study the hydroalcoholic extract of leaves of Amaranthus tricolor L. (HAEAT) 100, 200 and 400 mg/kg body weight was studied for anti-nociceptive and anti-inflammatory activities in various a...

OBJECTIVES Aim of the present work was to investigate the anti-inflammatory, analgesic and antiulcer effects of red seaweed Porphyra vietnamensis (P. vietnamenis). MATERIALS AND METHODS Aqueous (POR) and alcoholic (PE) fractions were successfully isolated from P. vietnamenis. Further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing in...

Analgesic and ulcerogenic properties have been studied for the copper(II) coordination complex of the nonsteroidal anti-inflammatory drug Fenoprofen and imidazole [Cu(fen)2(im)2] (Cu: copper(II) ion; fen: fenoprofenate anion from Fenoprofen, im: imidazole). A therapeutic dose of 28 mg/kg was tested for [Cu(fen)2(im)2] and 21 mg/kg was employed for Fenoprofen calcium, administered by oral gavage...

The analgesic effects of a series of muscarinic agonists were investigated by use of the mouse acetic acid writhing, grid-shock, hot-plate and tail-flick tests. The compounds tested were oxotremorine, pilocarpine, arecoline, aceclidine, RS86 and four 3-3(substituted-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahy-dro-1 -methyl pyridines (substituted TZTP), these being propoxy-TZTP, 3-Cl-propylthio-TZTP,...

Purpose: To investigate the active fraction of pomegranate fruit extract and screen it for analgesic activity. Methods: The analgesic activity of pomegranate ethyl acetate fraction (EtOAc) was examined using three models of pain: writhing, hot tail flick and plantar tests. EtOAc was administered by oral gavage in doses of 100, 150 and 200 mg/kg, p.o., for all the tests and compared to aspirin (...