background: super oxidized water (sow), as a novel antiseptic solution, is used with claims of effectiveness and cost effectiveness in healing chronic wounds such as diabetic foot, infectious post-operative ulcers and burn ulcers. we conducted a health technology assessment to evaluate the clinical evidence from clinical and randomized trials for this disinfection. this study aims to evaluate t...

INTRODUCTION Wound infection is a significant clinical challenge in hospitals in developing countries where proper healthcare delivery is hampered by limited resources. This study investigated the antibiotic susceptibility pattern of bacteria causing wound infection and risk factors for infection among hospitalized patients in Buea, Cameroon, to generate findings which could drive reformation o...

PROBLEM IDENTIFICATION Patients with malignant wounds report pain, distress from odor and exudate, decreased self-esteem, and poor quality of life. This systematic review explores topical opioids, antimicrobials, and odor-reducing agents for preventing or managing malignant wound pain, infection, and odor.
. LITERATURE SEARCH MEDLINE®, EMBASE, the Cochrane Library, CINAHL®, and reference list...

To the Editor: In reporting on the results of the Fluid Lavage of Open Wounds (FLOW) trial, Bhandari et al. (Dec. 31 issue)1 describe the initial management of open fracture wounds. According to their protocol, the investigators aimed to perform irrigation and débridement for skin and soft-tissue defects or to close wounds that had delayed union or nonunion with the use of grafting or muscle fl...

OBJECTIVE The aim of this study was to investigate efficacy of azithromycin versus cephalexin for infection prophylaxisis in patients with simple traumatic wounds managed at emergency department. METHOD This randomized controlled trial compared short-course therapy of once-daily azithromycin (500 mg before the wound repair followed by 250 mg/day for 5 days) with cephalexin (1000 mg before wou...

Negative pressure wound therapy (NPWT) is widely used to treat many types of complex wounds, and the advent of the instillation and dwell time (NPWTi-d) technique has enhanced this system with the addition of automated treatment with topical solutions. In the field of vascular surgery, NPWT is utilized to help close wounds over underlying grafts; however keeping these wounds free of infection a...

Pam Cooper, David Gray, Fiona Russell and Sandra Stringfellow are Clinical Nurse Specialists; John Timmons, Melvyn Bertram, Kristine Duguid, Gail Pirie and Evelyn Quinn are Tissue Viability Nurses, all at the Department of Tissue Viability, NHS Grampian, Aberdeen Wound care practice can be difficult to monitor due to the complex nature of wounds, the patients, the variety of dressings, and the ...

R Gary Sibbald is Professor, Medicine and Public Health Science; Director of Continuing Education, Department of Medicine, University of Toronto; Director of Dermatology, Daycare and Wound Healing Clinic, Sunnybrook and Women’s Health Sciences Centre; Toronto Wound Healing Centres, Toronto, Ontario; and Chairman (Toronto Meeting 2008) of the World Union of Wound Healing Societies. Adam Katchky ...

Chronic wounds are a significant burden to global patient and health care infrastructures, and there is a need for better methods of early wound diagnosis and treatment. Traditional diagnosis of chronic wound infection by pathogenic bacteria, using clinical signs and symptoms, is based on visual inspection under white light and microbiological sampling (e.g. swabbing and/or biopsy) of the wound...