mesenchymal stem cells (mscs) could differentiate into various types of tissues. these cells serve as a backup for the regeneration and repair of tissues or cells after injury. a skin wound is defined as an injury to the skin that needs to be restored. all types of cells in skin especially mesenchymal stem cells play important role in wound healing process. in particular, paracrine signaling of...

During the U. S. Civil War (1861-65) surgeons performed a vast number of surgical procedures. The efficacy of surgery has been continually debated since the war began, in part because of lack of evidence for the (in)effectiveness of surgery. I analyze data gathered by Dr. Edmund Andrews, a surgeon with the 1st Illinois Light Artillery. The data can be arranged as observational data on surgery a...

Our knowledge of patients' concerns with regard to living with chronic ulceration remains incomplete. This cross-sectional survey collected the self-reported views of patients using a specifically designed questionnaire developed from issues relevant to UK patients captured through focus groups. Results were obtained for 196 patients from Wales and England with a mean age of 74.4 years (SD 12...

OBJECTIVES/HYPOTHESIS Skin irritation and ulceration beneath the tracheostomy tube or ties secondary to pressure and shearing forces on the skin frequently complicate pediatric tracheotomy in the immediate postoperative period. The aim of this study is to determine the effectiveness of Mepilex Ag dressings in reducing posttracheotomy wound complications. STUDY DESIGN Retrospective study. ME...

The hand is the most common site for bite injuries. Because of specific characteristics of hand anatomy, bite mechanics, and organisms found in human and animal saliva, even small wounds can lead to aggressive infections. Failure to recognize and treat hand bites can result in significant morbidity. Human and animal bites most commonly lead to polymicrobial bacterial infections with a mixture o...

Pyoderma gangrenosum (PG) is an inflammatory disease characterized by recurrent painful ulcers, eventually leading to cribriform scars. PG mostly a diagnosis of exclusion with neutrophilic skin infiltration. We present case 35-year-old female patient whose first presentation occurred in the trimester pregnancy, which recurred after discontinuation breastfeeding. The also had history taking prol...

BACKGROUND Risk assessment forms a key component in self-harm management. Among self-harm presentations generally, lethality of an index act is a poor predictor of future non-fatal repetition. However, no study has examined whether severity of an index self-cutting episode is associated with prospective repetition. AIMS To examine factors associated with severity of self-cutting and in partic...

Ionizing radiation is an important treatment modality for a variety of malignant conditions. However, development of radiation-induced skin changes is a significant adverse effect of radiation therapy (RT). Cutaneous repercussions of RT vary considerably in severity, course, and prognosis. When they do occur, cutaneous changes to RT are commonly graded as acute, consequential-late, or chronic. ...

nowadays, hydrogels are widely used as wound dressings in biomedical applications. similar to other types of the moist (wet) wound dressings, it is necessary to have sufficient information about their dehydration kinetics during the pre-usage period (e.g. storage duration) and also the wound healing process. in this work, hydrogel wound dressings based on polyvinyl alcohol were prepared by cycl...