UNLABELLED Cavus foot surgeries are relatively common procedures in pediatric orthopedics. Following surgery, the tensile forces exerted on the wound by the newly corrected foot may hinder soft tissue healing and lead to wound dehiscence. Treatments including skin grafting and other plastic surgery procedures have been described in order to manage this complication. However, the effectiveness o...

Amputation as a result of impaired wound healing is a serious complication of diabetes. Inadequate angiogenesis contributes to poor wound healing in diabetic patients. Endothelial progenitor cells (EPCs) normally augment angiogenesis and wound repair but are functionally impaired in diabetics. Here we report that decreased expression of manganese superoxide dismutase (MnSOD) in EPCs contributes...

Lower-extremity wounds are a major complication of diabetes. Hemoglobin A1c (HbA1c) reflects glycemia over 2-3 months and is the standard measure used to monitor glycemia in diabetic patients, but results from studies have not shown a consistent association of HbA1c with wound healing. We hypothesized that elevated HbA1c would be most associated with poor wound healing. To test this hypothesis,...

T he diabetic foot syndrome represents a major problem in the health care of diabetic patients. Understanding the molecular basis of this disease is an important step toward a rational treatment. Due to the systemic character of diabetes, disturbances in several basic cell functions appear to contribute to impaired wound healing. Many essential processes of normal wound healing are regulated in...

The wound itself, along with lymphatic oedema, nausea and vomiting, fatigue psychological stress, is listed as one of the five factors most negatively influencing cancer patients. Current oncologic treatment strategies are based on multimo­dal protocols including surgery, radiation chemotherapeutic regimens. Thus, in oncology we can have a patient surgical wound, that complication from radio- o...

OBJECTIVES To prospectively determine the wound complication rate for dermatology inpatients undergoing diagnostic skin biopsies during their admission and to determine significant host and procedural risk factors. DESIGN Prospective assessment, by a single observer, of 100 postdiagnostic skin biopsy wounds in dermatology inpatients. The following data were recorded for each patient: age and ...

Postoperative wound infection is of great importance to both surgeon and patient. All surgeons know that postoperative wound infection means morbidity, anxiety, longer hospitalization, higher cost; not to forget the embarrassment to the surgeons. However, it is still a common surgical complication despite other advances in modern medicine. This study was conducted to find out the incidence of p...

BACKGROUND There are increasing reports of deaths and serious complications associated with the use of negative pressure wound therapy (NPWT), of which right ventricular heart rupture is the most devastating. The use of a rigid barrier has been suggested to offer protection against this lethal complication by preventing the heart from being drawn up against the sharp edges of the sternum. The a...

Diabetic foot ulcer (DFU) caused by impaired wound healing is a common vascular complication of diabetes. The current study revealed that plasma levels of pigment epithelium-derived factor (PEDF) were elevated in type 2 diabetic patients with DFU and in db/db mice. To test whether elevated PEDF levels contribute to skin wound-healing delay in diabetes, endogenous PEDF was neutralized with an an...

introduction : for many years surgical incisions were done by scalpel. nowadays this method has been replaced with electrocautery.each of these methods has their disadvantages and benefits. the purpose of this study is to compare these two methods in midline laparotomy surgeries. methods :  from 2012 until 2013, one hundred patients enter the study, underwent midline laparotomy and were divided...