results the i/r group showed a significant increase in pycnotic (dying) neurons and pretreatment with wc at doses of 500 mg/kg and 1000 mg/kg significantly reduced pycnotic and tunel positive neurons, in a dose dependent manner in ischemic brain cortex. conclusions our findings indicated that wc has neuroprotective effects and is able to reduce histopathological alterations and apoptosis in bra...

Introduction and Aim: Withania somnifera, called as Indian Ginseng is a very important plant in traditional medicinal practices. The possesses wide range of activity has been used to treat multiple diseases. anti-inflammatory, neuroprotective, hypoglycemic, antiarthritic, hepatoprotective, antioxidant, anti-stress, immunostimulatory anti-cancer therapeutic activities. Cancer health burden preva...

The incidence and the rate of progression of nondiabetic renal disease is generally greater in men compared with age-matched women, suggesting that the female sex is protective and/or that the male sex is a risk factor for the development and progression of nondiabetic renal disease. In diabetes, even though the male sex still appears to be a risk factor, this relationship is not as strong as i...

Plants have always been an indispensable part of human life since the beginning civilisation. Withania somnifera (L.) DUNAL, popularly known as Wintercherry or Indian Ginseng, is widely considered Ashwagandha. In Ayurveda, it classified a Rasayana (rejuvenation) and projected to promote mental physical health, rejuvenate body in debilitated conditions increase longevity. Due its beneficial chem...