A high-resolution climate archive was reconstructed based on carbon isotope analysis and radiocarbon dating of the Chapman baobab in northeastern Botswana. The baobab, which exhibited an open ring-shaped structure composed six stems, collapsed January 2016 during intense El Niño event. Two samples belonging to oldest stems were investigated order obtain a proxy rainfall record, provides insight...

Cancers are the major cause of death worldwide. Chemotherapy using cytotoxic drugs and targeted therapy is required when surgery is difficult, ineffective, or impossible. We previously synthesized the novel synthetic 1-benzylindole derivative 21-900 and found that it inhibits histone deacetylase (HDAC) activities and tubulin assembly. Here we tested its effects on the human leukaemia cell lines...

Background: The increasing use of telecommunication devices such as Wi-Fi modems and mobile phones in the recent years can change the cellular structure of microorganisms so the generation of electromagnetic waves has led to concern in the community whenever be exposed to these fields and may have harmful effects on human health.Material and Methods: Standard strains of bacteria were prepared o...

The aim of the research was to investigate the pharmacokinetics (PK) of enteric-coated mycophenolate sodium (EC-MPS) by quantification of the active metabolite of mycophenolic acid (MPA) after multiple escalating oral doses in Han kidney transplant recipients. A total of 28 Han postoperative kidney transplant recipients were given a multiple-dose of 540, 720 or 900 mg of EC-MPS two times a day ...

This paper describes a low-noise, 900-MHz, voltagecontrolled oscillator (VCO) fabricated in a 0.6m CMOS technology. The VCO consists of four-stage fully differential delay cells performing full switching. It utilizes dual-delay path techniques to achieve high oscillation frequency and obtain a wide tuning range. The VCO operates at 750 MHz to 1.2 GHz, and the tuning range is as large as 50%. Th...

The stability condition of a resonator formed by a 900 cone and mirror has been derived using ray tracing techniques. The result showed that this type of resonator is relatively insensitive to mirror misalignment. From this basis, the mirror misalignment tolerance was studied experimentally. Output energy and transverse mode characteristics vs. misalignment were measured, and the results show t...