bacground: wilson's disease is a rare autosomal recessive disorder characterized by toxic accumulation of copper in liver and brain. the disorder is caused by mutations in the atp7b gene, encoding a copper transporting p-type atpase. characterization of the spectrum of mutations in this gene is important both for diagnosis and genetic counseling of the families.materials and methods: we en...

We study the two-dimensional lattice Gross–Neveu model with Wilson twisted mass fermions in order to explore the phase structure in this setup. In particular, we investigate the behaviour of the phase transitions found earlier with standard Wilson fermions as a function of the twisted mass parameter μ. We find that qualitatively the dependence of the phase transitions on μ is very similar to th...

The simulation of surface flow dynamics using a flow-path network model Yumin Chen, Qiming Zhou, Sheng Li, Fanrui Meng, Xiaomei Bi, John P. Wilson, Zisheng Xing, Junyu Qi, Qiang Li & Chengfu Zhang To cite this article: Yumin Chen, Qiming Zhou, Sheng Li, Fanrui Meng, Xiaomei Bi, John P. Wilson, Zisheng Xing, Junyu Qi, Qiang Li & Chengfu Zhang (2014) The simulation of surface flow dynamics using ...

I was introduced to neurobiology, first by Don Kennedy, a great role model as a brilliant teacher-researcher, and later by Don Wilson, the genius behind the role of central rhythm generators in behavior. Kennedy and Wilson showed how much we have to learn about brains from studying the brain and behavior of invertebrate animals. Eric Kandel, Seymour Benzer, and Sydney Brenner inspired many of u...

The Box-Wilson central composite design (CCD) based on response surface methodology (RSM) was used for ethanol fermentation using very high gravity (VHG) finger millet hydrolysate. Optimized process variables were namely, concentrations of yeast extract, magnesium sulphate and pH of the medium. High gravity mashes (>300 g dissolved solids per liter) were prepared by a thermo-stable α-amylase, f...

In this note we discuss local gauge-invariant operators in noncommutative gauge theories. Inspired by the connection of these theories with the Matrix model, we give a simple construction of a complete set of gauge-invariant operators. We make connection with the recent discussions of candidate operators which are dual to closed strings modes. We also discuss large Wilson loops which in the lim...

Some consequences which follow from the periodicity assumption for spectral density of Wilson–Dirac operator are studied. Such an assumption allows to obtain simple representations for quark propagator, which reveals an important role of m ↔ −m symmetry. It is argued that this symmetry is restored when the mirror fermion mass mr tended to infinity. The constrains on zero modes of Wilson–Dirac o...

We review our recent proposal for a new lattice action for non-abelian gauge theories which reduces short-range lattice artifacts in the computation of the topological susceptibility. The standard Wilson action is replaced by the Wilson action of a gauge covariant interpolation of the original fields to a finer lattice. We illustrate the improved behavior of a same-philosophy new lattice action...

Double–lepton polarization asymmetries in Λb → Λl+l− decay are calculated using a general, model independent form of the effective Hamiltonian. The sensitivities of these asymmetries to the new Wilson coefficients are studied in detail. Furthermore, the correlations between averaged double–lepton polarization asymmetry and branching ratio are analyzed. It is shown that there exist certain regio...

Wilson disease is a metabolic disorder with an autosomal recessive genetic pattern and occurs in 1-4 of every 100000 individuals. Inactivation of the ATP7B gene leads to accumulation of the toxic copper to liver and brain causing hepatic and neurological complication. Therefore, most patients suffer from chronic hepatic inflammation and central nervous system disorder. Nowadays, up to ...