introduction: previous studies have been shown that low frequency stimulation (lfs) has an inhibitory effect on kindling acquisition. however, the mechanism of this effect has not been completely determined. in the present study, the effect of lfs of the perforant path on seizures induced by rapid perforant path kindling was investigated. methods: animals were kindled by electrical stimulation ...

conclusions when itbs was applied over the primary motor cortex, it significantly improved manual dexterity, but had no significant effect on the hand motor imagery ability in ms patients. results itbs group showed a reduction in the time required to complete the 9hpt (mean difference = -3.05, p = 0.002), and an increase in the number of blocks transferred in one minute in the bbt (mean differe...

introduction fetal movement started at the 7th weeks of pregnancy and by the end of pregnancy will gradually be perfect and harmonious. near-term fetuses can discriminate acoustic features, such as frequencies and spectra, and process complex auditory streams. in this study, we aimed to evaluate fatal movement in response to music and vibration stimulation. materials and methods this study is a...

the provision of an adequate quantity of cells with proper function and purity is one of the main challenges of tissue engineering studies. stem cells, with their self-renewal and differentiation capacity, are considered one of the main cell sources in the field of tissue engineering. previously, the use of chemical factors seemed to be the only possible way for stem cell differentiation. howev...

epilepsy is among the most common disorders of the central nervous system and there is not an absolute method for its treatment. it has been shown that each seizure has a depressing effect on the following seizure. thus, finding the mechanisms responsible in this phenomenon can improve our knowledge toward new ways for epilepsy treatment. in this study, the role of adenosine a1 receptors in pos...

Background: Breastfeeding failures and oral feeding problems in preterm infants result in long-term health complications. In this study, therefore, we aimed to evaluate the effect of oral stimulation along with non-nutritive sucking (NNS) on independent oral feeding initiation and weight gain in preterm infants. Methods: This prospective randomized clinical trial was carried out at Aliasghar Ho...

Stimulation of peripheral cranial nerves has been shown to exert anticonvulsant effects in animal models as well as in human patients. Specifically, stimulation of both the trigeminal and vagus nerves has been shown in multiple clinical trials to be anticonvulsant, and stimulation of these nerves at therapeutic levels does not cause pain or negatively affect brain function. However, the neurona...

advantages of mild-stimulation have long been appreciated, while there was a called for more patient-friendly approach in ovarian stimulation around 20 years ago (1)...