Introduction: Typhoid fever is a global health problem, causing significant morbidity and mortality throughout the developing world. A recent survey estimated a global number of 21.7 million illnesses and 217.000 deaths in the year 2000. Due to poverty and poor sanitary conditions, typhoid fever remains a major health problem in Nepal. A frequent complication of typhoid fever is perforation of ...

Corticosteroids are used in the treatment of many rheumatological diseases including temporal arteritis. The gastrointestinal perforation during corticosteroid treatment is a serious complication. Colon perforation after steroid use was first reported by Beck et al in 1950.1 Although the pathophysiological mechanism is not understood clearly, it is claimed that steroids probably by disturbing t...

UNLABELLED Gastrointestinal perforation is a complication associated with steroid therapy or hypercortisolism, but it is rarely observed in patients with Cushing's disease in clinical practice, and only one case has been reported as a presenting symptom. Herein, we report a rare case of Cushing's disease in which a patient presented with gastrointestinal perforation as a symptom. A 79-year-old ...

Acute cholecystitis leading to gallbladder perforation is relatively common. However, transhepatic perforation of the gallbladder leading to biliary peritonitis is very rare. We present a rare case of biliary peritonitis caused by transhepatic perforation of the gallbladder.

BACKGROUND Colonic perforation is a rare complication associated with colonoscopy. There are no population-based studies on the risk of colonic perforation in IBD inpatients. AIM We sought to determine the prevalence of colonic perforation during colonoscopy among IBD inpatients, and to assess its risk factors. MATERIALS AND METHODS We obtained patient data from the Nationwide Inpatient Sam...

BACKGROUND The intrauterine device is a popular form of long-acting reversible contraception. Although generally safe, one of the most serious complications of intrauterine device use is uterine perforation. Risk factors for perforation include position of the uterus, force exerted during intrauterine device insertion, postpartum period, and breastfeeding. This case is important and needs to be...

BACKGROUND/AIMS Esophageal perforation is a rare but often a life-threatening condition. However, the incidence and clinical features of esophageal perforation caused by ingested foreign body are unknown. This study investigated the incidence of esophageal perforation caused by ingested foreign body and evaluated the clinical features and outcome of patients with esophageal perforation. METHO...

ventriculoperitoneal (vp) shunt placement that diverts the cerebrospinal fluid (csf) into the peritoneal cavity is the most common method of treatment of hydrocephalus. this shunt has a high incidence of malfunction mainly due to catheter obstruction or infection. about 20% of these complications are abdominal that may occur at any time after shunt placement from 1 week to several years. this s...

Endoscopic closure techniques have been introduced for the repair of duodenal wall perforations that occur during endoscopic retrograde cholangiopancreatography (ERCP). We report a case of successful repair of a large duodenal wall perforation by using double endoscopic band ligation (EBL) and an endoclip. Lateral duodenal wall perforation occurred during ERCP in a 93-year-old woman with acute ...

BACKGROUND/AIMS Some factors like stent wires, balloon dilatation and use of guide wires seems to increase perforation after self-expandable metal stent (SEMS) placement, but few studies mentioned about the relationship between angulation of malignant stricture and perforation. The present study aimed to confirm that more angular positioning of stents increases perforation. METHODS This study...